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Vesicle size, size distribution, stability, and rheological properties of liposomes coated with water-soluble chitosans of different molecular weights and concentrations


, : Vesicle size, size distribution, stability, and rheological properties of liposomes coated with water-soluble chitosans of different molecular weights and concentrations. Journal of Liposome Research 11(2-3): 211-228

The objectives of this study were to explore the effects of coating with water-soluble chitosans of different molecular weights and concentrations on vesicle size, size distribution, stability, and apparent viscosity of liposomes. The results indicate that the vesicle size of liposomes coated with different concentrations and different molecular weights of water-soluble chitosans decreased with increasing passes of microfluidizing treatment, then reached a constant value. Liposomes subjected to the same microfluidization treatment were larger for those coated with a higher concentration (of the same molecular weight chitosan) or coated with a lower molecular weight (at the same concentration) of water-soluble chitosans. The average particle size of liposomes coated with different molecular weights of water-soluble chitosans decreased with increasing number of passes of microfluidizing treatment. The apparent viscosity of liposomes coated with water-soluble chitosans decreased after the first pass, then reached a constant value after the third pass of microfluidizing treatment. Apparent viscosities of liposomes subjected to different passes of microfluidization treatment were larger for those coated with a higher concentration or a higher molecular weight of water-soluble chitosans. Liposomes coated with 0.5% of different molecular weights of water-soluble chitosans behaved as pseudoplastic fluids. At the same shear rate, the apparent viscosities of liposomes subjected to more passes of microfluidizing treatment were larger than those subjected to fewer passes of microfluidizing treatment. Liposomes coated with water-soluble chitosans are more stable than those without a coating.

US$19.90

PMID: 19530934

DOI: 10.1081/LPR-100108463


Other references

Bianciotto, V.; Minerdi, D.; Perotto, S.; Bonfante, P., 1996: Cellular interactions between arbuscular mycorrhizal fungi and rhizosphere bacteria. We have investigated whether direct physical interactions occur between arbuscular mycorrhizal (AM) fungi and plant growth promoting rhizobacteria (PGPRs), some of which are used as biocontrol agents. Attachment of rhizobia and pseudomonads to the...

Cochec, F. le; Soreau, P., 1992: Heterosis and inheritance of four agronomic characters in fodder beet and sugarbeet (Beta vulgaris L.) inbred line crosses. Parents, F1, F2, BC1 and BC2 generations of 2 crosses (OLI x 561-20 and RVE x 569-31) between fodder beet and sugarbeet inbred lines, respectively, were evaluated for root weight, and dry matter percentage and dry matter yield. Root colour was stu...

Członkowska, A.; Tarnacka, B.; Möller, J.Carsten.; Leinweber, B.; Bandmann, O.; Woimant, F.; Oertel, W.H., 2007: Unified Wilson's Disease Rating Scale - a proposal for the neurological scoring of Wilson's disease patients. The clinical forms of Wilson's disease (WD) neurological manifestations can be divided into three movement disorder syndromes: a) dystonic, b) ataxic, c) parkinsonian syndrome. These syndromes in WD seldom occur in isolation. Clinical rating...

Dubinsky, M.; Reyes, E.; Ofman, J.; Chiou, C.F.ng; Wade, S.; Sandborn, W.J., 2003: Cost-effectiveness analysis of thiopurine methyltransferase screening and metabolite monitoring in the management of azathioprine Treated Crohns disease patients. American Journal of Gastroenterology 98(9 Supplement): S233, September

Messina, A.; Nannelli, A.; Fiorio, R.; Longo, V.; Gervasi, P.G., 2009: Expression and inducibility of CYP1A1, 1A2, 1B1 by beta-naphthoflavone and CYP2B22, 3A22, 3A29, 3A46 by rifampicin in the respiratory and olfactory mucosa of pig. The presence and inducibility of specific CYPs (1A1, 1A2, 1B1, 2B22, 3A22, 3A29 and 3A46) and the related transcriptional factors (AhR, CAR, PXR, and HNF4alpha) were investigated, at activity and/or transcriptional level, in liver, respiratory and...

Watała, C.; Bryszewska, M.; Stefaniak, B.; Nowak, S., 1986: Peroxide metabolism enzymes in diabetic children: relationship to duration and control of diabetes. Enzyme activities of erythrocyte superoxide dismutase (SOD), peroxidase and catalase in groups of diabetic children, the duration of the disease and control qualities were compared with respective values obtained for healthy children. Generally th...

Vajda, F.J.E.; Horgan, D.; Hollingworth, S.; Graham, J.; Hitchcock, A.A.; Roten, A.; O'Brien, T.J.; Lander, C.M.; Eadie, M.J., 2012: The prescribing of antiepileptic drugs for pregnant Australian women. It is not clear how widely it is appreciated in Australia that certain antiepileptic drugs, particularly valproate, are teratogenic. The aim of the study is to assess trends in the pattern of antiepileptic drug prescribing for pregnant women in Au...

Lovati, A.; Mura, A., 1949: Nuclear interactions of the particles produced in cosmic ray bursts. Nature 163(4156): 1004-1006

Chun, Y.Sook.; Kim, K.Woo.; Kim, J.Chan., 2014: Autologous tragal perichondrium patch graft for ahmed glaucoma valve tube exposure. To describe a novel method of repair for an exposed Ahmed valve tube using tragal perichondrium. A 56-year-old man with a severe chemical burn was referred to our clinic for the management of total limbal stem cell deficiency. During the treatment...

Singh, A.P.; Bhargava, S.N., 1976: Presence of some antifungal substance in the skin of guava fruits (Psidium guajava L.). The skins of some guava cvs. contain antifungal substances inhibitory to the germination of post harvest pathogens.