+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta4Gal-T1cntdotLA complex with UDP-Glc

, : Alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta4Gal-T1cntdotLA complex with UDP-Glc. Journal of Biological Chemistry 276(40): 37665-37671

beta-1,4-Galactosyltransferase 1 (Gal-T1) transfers galactose (Gal) from UDP-Gal to N-acetylglucosamine (Glc-NAc), which constitutes its normal galactosyltransferase (Gal-T) activity. In the presence of alpha-lactalbumin (LA), it transfers Gal to Glc, which is its lactose synthase (LS) activity. It also transfers glucose (Glc) from UDP-Glc to GlcNAc, constituting the glucosyltransferase (Glc-T) activity, albeit at an efficiency of only 0.3-0.4% of Gal-T activity.


Other references

Tirlet, G., 1991: Grooved bonded bridges. Protocols for fabrication and bonding. Les Cahiers de Prothese 76: 108-113

Voelker, D.; Clarke, R., 1988: Illinois: ground-water quality. Geological survey water supply paper: 325) 237-244

Saillard C.; Vignault J.C.; Bove J.M.; Raie A.; Tully J.G.; Williamson D.L.; Fos A.; Garnier M.; Gadeau A.; E.A., 1987: Spiroplasma phoeniceum new species a new plant pathogenic species from syria. Sixteen spiroplasma isolates, recovered over a 2-year period from symptomatic periwinkle plants (Catharanthus roseus) collected in eight different locations in Syria, were compared with other established Spiroplasma species or serogroups. Serologi...

Lundquist, F.; Galatius, J.Nsen, H., 1960: Quantitative determination of amino acids by combined displacement- and paper chromatography. Scandinavian Journal of Clinical and Laboratory Investigation 12: 342-352

Achiron, A.; Kuritzky, A., 1990: Dysphagia as the sole manifestation of adult type I Arnold-Chiari malformation. Neurology 40(1): 186-187

Chen, B.Y.; Heneen, W.K.; Sominsen, V., 1989: Comparative and genetic studies of isozymes in resynthesized and cultivated brassica napus l. brassica campestris l. and brassica alboglabra bailey. Enzyme electrophoresis was used to compare newly resynthesized Brassica napus with its actual parental diploid species, B. campestris and B. alboglabra. Comparisons were also made with cultivated B. napus. Of the eight enzyme systems assayed, four...

Wu, K-Hsi.; Chang, J-Gowth.; Ho, Y-Jen.; Wu, S-Fen.; Peng, C-Tien., 2006: Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major. Patients with beta-thalassemia (thal) major are subject to Peroxidative tissue injury by iron overload. Glutathione S-transferases work as antioxidants, and their activity is determined genetically. In this study, we used)multiplex polymerase chai...

Morales, A.M.; Fernandez, C.; Rodriguez, Y.; Diaz, J.C., 2004: Herbicide efficacy and sugarcane tolerance before Kalif EC 48 (clomazone). Three trials were conducted to assess the efficacy of the new herbicide formulation Kalif EC 48 (clomazone) in controlling weeds infesting sugarcane such as Leptochloa panicea, Digitaria adscendens [D. ciliari], Rottboellia cochinchinensis, Sorghu...

Myhre, B.A.; Nakasako, Y.Y.; Schott, R.; Johnson, D.; Berkman, R.M.; Cleland, E.L., 1978: An aseptic fluid transfer system for blood and blood components. A device is described which can be attached to all blood bags. Two of these devices are heat-sealed together aseptically at any time during the storage life of the blood unit, and an opening connecting the 2 is created. In vitro and in vivo studie...

Gopakumar, A.; Sreedharan, J.; Premadasa, G.; Muttappallymyalil, J., 2014: Empathy levels among first year Malaysian medical students: an observational study. Advances in Medical Education and Practice 5: 237-239