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A convenient preparation of (1R,2S,7S,8R)-3,5-,diaza-2,7-dimethyl-1,8diphenyloctan-1,8-diol and its enantiomer

, : A convenient preparation of (1R,2S,7S,8R)-3,5-,diaza-2,7-dimethyl-1,8diphenyloctan-1,8-diol and its enantiomer. Chemical and Pharmaceutical Bulletin (Tokyo) 54(9): 1331-1332

The synthesis of (1R,2S,7S,8R)-3,5-diaza-2,7-dimethyl-1,8-diphenyloctan-1,8-diol 6 and its enantiomer 7 are described utilising (-)-(1R,2S)- or (+)-(1S,2R)-norephedrine, respectively.


PMID: 16946547

DOI: 10.1248/cpb.54.1331

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