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A convenient synthesis of an anti-Helicobacter pylori agent, dehydrodiconiferyl alcohol

, : A convenient synthesis of an anti-Helicobacter pylori agent, dehydrodiconiferyl alcohol. Archives of Pharmacal Research (Seoul) 29(7): 563-565

Potential anti-Helicobacter pylori agent dehydrodiconiferyl alcohol was synthesized in 44% overall yield, starting from vanillin which could be commercially available. Carbon extension of vanillin followed by the Horner-Wadsworth-Emmons reaction, a biomolecular radical coupling reaction and DIBAL-H reduction gave dehydrodiconiferyl alcohol.


PMID: 16903075

DOI: 10.1007/bf02969265

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