geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Apoptotic pathways in ischemic acute renal failure


, : Apoptotic pathways in ischemic acute renal failure. Kidney International 66(2): 500-506

The study of cell death has emerged as an important and exciting area of research in cell biology. Although two kinds of cell death, apoptosis and necrosis, are recognized, one of the major advances in our understanding of cell death has been the recognition that the pathways traditionally associated with apoptosis may be very critical in the form of cell injury associated with necrosis. Renal tubular epithelial cell injury from ischemia has been generally regarded as a result of necrotic form of cell death. We briefly describe recent evidence indicating that pathways generally associated with apoptosis, including endonuclease activation, role of mitochondria and caspases, are important in renal tubular injury. It is likely that the cascades that lead to apoptotic or necrotic mode of cell death are activated almost simultaneously and may share some common pathways.

US$19.90

PMID: 15253697

DOI: 10.1111/j.1523-1755.2004.761_6.x


Other references

Mei ZhiSheng, 2001: Current situation of research and development of Tibetan medicine and suggestion for industrialization of traditional Tibetan medicine. In the past few years, traditional Tibetan medicine (TTM) has received considerable attention in the research and development sectors. Twenty-three Tibetan remedies were included in the Chinese Pharmacopoeia (published in 2000). Many pharmaceutica...

Sato, O.; Sugita, K.; Ookochi, Y.; Suzuki, M.; Umei, M., 1974: Lesion of the median longitudinal fasciculus following head injury. Neurochirurgia 17(4): 141-145

Bowen Bruce E.; Vondra Carl F., 1974: Paleoenvironmental interpretations of the upper Cenozoic sediments, east Lake Rudolf, Kenya. Abstracts with Programs - Geological Society of America 6(7): 664

Combacal, C., 1983: A new topworking technique for grapevines. Cleft grafting on 2 shoots/plant is carried out at the end of March, using long (5 bud) scions previously treated with paraffin wax. The graft union is protected by an inverted bottomless plastic bottle filled with soil or river sand. The bottle n...

Franke, H.J., 1995: Stochastic modelling of regional transport processes: modelling concept and field application to nitrate transport. The regional modelling of solute transport requires the consideration of data uncertainty or data variability. Usually, this uncertainty is introduced into the modelling process by a well-known sensitivity analysis. But in investigating questions...

Yeh, F.L.ng; Yan, H.L.ng; Wang, S.Y.; Jung, T.Y.; Hsu, T., 2003: Molecular cloning of zebrafish MutS homolog 6 and noncoordinate expression of MSH6 gene activity and G-T mismatch binding proteins in zebrafish larvae. Eukaryotic MutS homolog 6(MSH6) is a DNA mismatch recognition protein associated with mismatch repair of simple base-base mispairs and small insertion-deletion loops. As replication or recombination errors generated during embryonic development of...

Qiang, M.; Fenfang, W.; Yan, G.; Wen, S.; Maoliang, H.; Yingsong, W.; Weiwen, X.; Ming, L., 2011: Preparation and characterization of monoclonal antibody against translationally controlled tumor protein. From our previous proteomic research, we found that translationally controlled tumor protein (TCTP) might play at least a partial role in colon adenocarcinoma progression. However, the precise impact of TCTP on colorectal cancer metastasis progres...

Matusali, G.; Arena, G.; D.L.o, A.; D.R.nzo, L.; Mattia, E., 2009: Inhibition of p38 MAP kinase pathway induces apoptosis and prevents Epstein Barr virus reactivation in Raji cells exposed to lytic cycle inducing compounds. EBV lytic cycle activators, such as phorbol esters, anti-immunoglobulin, transforming growth factor beta (TGFbeta), sodium butyrate, induce apoptosis in EBV-negative but not in EBV-positive Burkitt's lymphoma (BL) cells. To investigate the mo...

Falconi, M.; Biocca, S.; Novelli, G.; Desideri, A., 2007: Molecular dynamics simulation of human LOX-1 provides an explanation for the lack of OxLDL binding to the Trp150Ala mutant. Background: Dimeric lectin-like oxidized low-density lipoprotein receptor-1 LOX-1 is the target receptor for oxidized low density lipoprotein in endothelial cells. In vivo assays revealed that in LOX-1 the basic spine arginine residues are importa...

SARAVAL.U.; Brunetti, F., 1955: Prim. Prof. Federico Brunetti. Rivista Italiana di Stomatologia 10(2): 176-180