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Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides

, : Capsule polysaccharide mediates bacterial resistance to antimicrobial peptides. Infection and Immunity 72(12): 7107-7114

The innate immune system plays a critical role in the defense of areas exposed to microorganisms. There is an increasing body of evidence indicating that antimicrobial peptides and proteins (APs) are one of the most important weapons of this system and that they make up the protective front for the respiratory tract. On the other hand, it is known that pathogenic organisms have developed countermeasures to resist these agents such as reducing the net negative charge of the bacterial membranes.


PMID: 15557634

DOI: 10.1128/IAI.72.12.7107-7114.2004

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