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Cellular reaction to hypoxia: sensing and responding to an adverse environment

, : Cellular reaction to hypoxia: sensing and responding to an adverse environment. Mutation Research 569(1-2): 87-100

Multicellular organisms have developed sophisticated physiologic mechanisms by which they maintain their tissues at the optimal oxygen concentration. This level is important so that the benefits of free oxygen can be realized, while limiting the potential harms. Despite these efforts, there exist physiologic and pathophysiologic conditions where oxygen delivery drops below what is necessary for the tissue.


DOI: 10.1002/chin.200513286

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