+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Damage in transition

, : Damage in transition. Trends in Biochemical Sciences 30(2): 63-66

Double-stranded DNA breaks (DSBs) are a particularly dangerous form of DNA damage because they can lead to chromosome loss, translocations or truncations. When DSBs occur, many proteins are recruited to the break site; these proteins serve to both initiate DNA repair and to activate a checkpoint response.


PMID: 15691649

DOI: 10.1016/j.tibs.2004.12.004

Other references

Bonduriansky, R., 2012: Sexual selection and conflict as engines of ecological diversification. Ecological diversification presents an enduring puzzle: how do novel ecological strategies evolve in organisms that are already adapted to their ecological niche? Most attempts to answer this question posit a primary role for genetic drift, which...

Savige, J.A.; Birch, D.F.; Fairley, K.F., 1983: Comparison of mid catheter collection and suprapubic aspiration of urine for diagnosing bacteriuria due to fastidious micro-organisms. We examined 40 female patients for the presence of fastidious bacteria in the bladder by culture of mid catheter and suprapubic aspiration urine specimens. Gardnerella vaginalis and Ureaplasma urealyticum were the most frequently isolated fastidio...

Walsh, M.D.; Dent, O.F.; Young, J.P.; Wright, C.M.; Barker, M.A.; Leggett, B.A.; Bokey, L.; Chapuis, P.H.; Jass, J.R.; Macdonald, G.A., 2009: HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological Stage C colorectal cancers. Predicting patient outcome for colorectal carcinoma (CRC) with lymph node but not distant metastases remains challenging. Various prognostic markers have been identified including microsatellite instability (MSI) and possibly expression of the MHC...

Saunders D.S., 1979: External coincidence and the photo inducible phase in the sarcophaga argyrostoma photoperiodic clock. Data from single light pulse resetting experiments on the circadian rhythm of pupal eclosion in S. argyrostoma were used to design and predict the outcome of 1- and 2-pulse cycles in terms of the induction of pupal diapause. Experiments were inter...

Thompson, T.J.; Owens, P.D.; Wilson, D.J., 1989: Intramembranous osteogenesis and angiogenesis in the chick embryo. Membrane bone formation was examined in the developing chick frontal bone of Stage 32-36 embryos using alizarin red whole mounts, wax and resin histology, transmission electron microscopy and India ink injection techniques. Mineralised bone was se...

Bogdan, N., 1981: Culture of sallow horn (Hippophae rhamnoides L.) on the degraded plots of land in Vrancea. Results and prospects. Revista padurilor industria lemnului celuloza si hirtie silvicultura si exploatarea padurilor 96(5): 291-295

Ikerd, J., 2005: My top ten reasons for eating local. Small farm today- 22(4): 22-24

Gillott, Cedric., 2005: Alfred Pibus Arthur 1924-2005. Entomological Society of Canada Bulletin. June; 372: 104

Laine, R.A.; Yoggeswaran, G.; Hakorori, S., 1974: Glycosphingolipids covalently linked to agarose gel or glass beads. Use of the compounds for purification of antibodies directed against globoside and hematoside. Journal of Biological Chemistry 249(14): 4460-4466

Neugut R.H., 1981: Epidemiological appraisal of the literature on the fetal alcohol syndrome in humans. An evaluation of the evidence regarding the association between heavy maternal alcohol intake during pregnancy and the occurrence in offspring of that cluster of abnormalities called the Fetal Alcohol Syndrome [FAS] is undertaken from an epidemiol...