geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Dynamic morphology of clear corneal cataract incisions


, : Dynamic morphology of clear corneal cataract incisions. Ophthalmology 110(12): 2342-2348

Objective: Clear corneal cataract incisions without sutures allow for rapid visual rehabilitation after phacoemulsification but might be associated with an increased risk of postoperative infection. The goal of this study was to examine in vitro dynamic changes in unhealed clear corneal cataract incisions that might adversely affect the risk of intraocular infection. Design: Laboratory investigation. Methods: Self-sealing clear corneal incisions were created in cadaveric human and rabbit eyes, and intraocular pressure was controlled with an infusion cannula. Incisions were imaged in real time using optical coherence tomography as intraocular pressure was varied. Using an artificial anterior chamber, India ink was applied to the surface of cadaveric human corneas with clear corneal incisions to detect possible flow of surface fluid along the incision. Intraocular pressure was varied by raising and lowering the infusion bottle so as to simulate the variation in intraocular pressure that would occur with successive blinks. Results: Optical coherence tomography demonstrated variation of corneal wound morphology in response to changes in intraocular pressure. Higher intraocular pressures were associated with close apposition of the wound edges, with no tendency for wound leakage. At low intraocular pressures, however, wound edges tended to gape, starting at the internal aspect of the wound. One incision opened along the entire length, allowing fluid flow across the cornea. Histologic examination revealed India ink particles in all incisions for up to three fourths of the length of the wound. Conclusions: Transient reduction of intraocular pressure might result in poor wound apposition in clear corneal incisions, with the potential for fluid flow across the cornea and into the anterior chamber, with the attendant risk of endophthalmitis.

US$19.90

PMID: 14644716

DOI: 10.1016/S0161-6420(03)00733-4


Other references

Uchio, S.; Sakamoto, K.; Terada, M.; Kiuchi, E., 1975: Criteria of evaluation of clinical training. A rating list and its keys. Japanese Journal of Nurses' Education 16(8): 459-465

Henry, C.W.; Williams, W.P., 1980: The detrimental effect of vaccinating parentally immune broilers with a modified liver virus vaccine for infectious bursal disease. The experiment involved 392,955 broilers from breeders vaccinated with a commercially available killed infectious bursal disease (KIBD) virus vaccine (Treatments 1 and 2) and 373,371 broilers from breeders not vaccinated with a KIBD virus vaccine...

Barber, Clifton E., 1993: Spousal care of Alzheimers disease patients in nursing home versus in-home settings Patient impairment and caregiver impacts. Clinical Gerontologist 12(4): 3-30

Bartek, M.J.; Vekshteyn, M.; Boarman, M.P.; Gallo, D.G., 1987: Liquid chromatographic determination of sotalol in plasma and urine employing solid-phase extraction and fluorescence detection. A liquid chromatographic method using a solid-phase extraction procedure for the quantification of sotalol in plasma and urine is described. Sotalol is eluted from an extraction column with ethyl acetate-acetonitrile (1:2) and, after separation by...

Lee, Y.Jin.; Lim, Y.Wook.; Yang, J.Yeon.; Kim, C.Soo.; Shin, Y.Chul.; Shin, D.Chun., 2011: Evaluating the PM damage cost due to urban air pollution and vehicle emissions in Seoul, Korea. This study evaluated the prospective damage costs of PM(2.5) inhalation. We performed a health risk assessment based on an exposure-response function to estimate the annual population risk in the Seoul metropolitan city, Korea. Also, we estimated...

Mander, J.V.; Jacob, G.A.; Götz, L.; Sammet, I.; Zipfel, S.; Teufel, M., 2015: Associations between Grawe's general mechanisms of change and Young's early maladaptive schemas in psychotherapy research: a comparative study of change processes. The study aimed at analyzing associations between Grawe's general mechanisms of change and Young's early maladaptive schemas (EMS). Therefore, 98 patients completed the Scale for the Multiperspective Assessment of General Change Mechanis...

Ogilvie Grant, W.R., 1915: Scottish Crested Titmouse in east Ross-shire. Brit London: 182-183

Abdel Wahab, M.M.; Maher, K.M.; Osman, M.A., 2016: The prognostic value of radiological bio-markers for detection of cerebral glioma grades and early evaluation of tumor response to radiation therapy using MRI perfusion and spectroscopy. Journal of Clinical Oncology 26(15_suppl): 13015-13015

Rubin, R.T.; Wheeler, N.C.; Pregibon, D.; Poland, R.E., 1988: Neuroendocrine aspects of primary endogenous depression. VII. Logistic regression analysis of matched patient-control hormone data for discrimination between groups. We previously reported significant alterations in hypothalamo-pituitary-adrenal cortical (HPA) and thyroid (HPT) axis function in a group of 40 primary, RDC definite endogenous depressives compared to 40 individually matched normal control subject...

Akiyoshi M., 1977: Evaluation of oto toxicity and safety of amino glycoside antibiotics in the guinea pig. Kuemmerle, Helmut P , Takeshi K Shibuya And Eiichi Kimura (Ed ) Advances in Clinical Pharmacology, Vol 13 Problems Of Clinical Pharmacology in Therapeutic Research: Phase I Proceedings Of The 14th International Symposium on Clinical Pharmacology Tokyo, Japan, July 1976 Xii+420p Illus Urban And Schwarzenberg: Baltimore, Md , Usa; Munich, West Germany Isbn 0-8067-0113-7; Isbn 3-541-70113-7 374-386