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ERCC4 associated with breast cancer risk: a two-stage case-control study using high-throughput genotyping

, : ERCC4 associated with breast cancer risk: a two-stage case-control study using high-throughput genotyping. Cancer Research 66(19): 9420-9427

The failure of linkage studies to identify further high-penetrance susceptibility genes for breast cancer points to a polygenic model, with more common variants having modest effects on risk, as the most likely candidate. We have carried out a two-stage case-control study in two European populations to identify low-penetrance genes for breast cancer using high-throughput genotyping.


PMID: 17018596

DOI: 10.1158/0008-5472.CAN-06-1418

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