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Effects of novel compound C333H on glucose and lipid metabolism


, : Effects of novel compound C333H on glucose and lipid metabolism. Zhongguo Yaolixue Tongbao 22(6): 667-670

Aim To investigate the effects of the novel compound C333H on reduce blood glucose and lipid in vivo. Methods Normal KM mice, hyperlipidaemia mice and type 2 diabetic mice by intragastric gavage were used and total RNA from liver, adipose and skeletal muscle were isolated for RT-PCR. Results C333H reduced blood lipid level and improved glucose metabolism. In addition, C333H increased expressions of LPL, aP2 and GluT4 at transcriptional level.

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