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Formulation and evaluation of aerosolized celecoxib for the treatment of lung cancer


, : Formulation and evaluation of aerosolized celecoxib for the treatment of lung cancer. Pharmaceutical Research 22(3): 427-439

Purpose. We examined the effect of aerosolized celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on the in vitro cytotoxicity and apoptotic response of docetaxel against the human lung carcinoma cell lines A549 and H460.Methods. A metered dose inhaler (MDT) formulation of celecoxib was prepared and evaluated for its medication delivery and aerodynamic properties.

US$19.90

PMID: 15835749

DOI: 10.1007/s11095-004-1881-z


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