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High-resolution MRI: in vivo histology?


, : High-resolution MRI: in vivo histology?. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 361(1465): 137-146

For centuries scientists have been fascinated with the question of how the brain works. Investigators have looked at both where different functions are localized and how the anatomical microstructure varies across the brain surface. Here we discuss how advances in magnetic resonance imaging (MRI) have allowed in vivo visualization of the fine structure of the brain that was previously only visible in post-mortem brains. We present data showing the correspondence between definitions of the primary visual cortex defined anatomically using very high-resolution MRI and functionally using functional MRI. We consider how this technology can be applied to allow the investigation of brains that differ from normal, and what this ever-evolving technology may be able to reveal about in vivo brain structure in the next few years.

US$19.90

PMID: 16553313

DOI: 10.1098/rstb.2005.1777


Other references

Yamamoto, J.; Tanaka, H., 2004: Dynamic control of the photonic smectic order of membranes. Self-assembled soft matter is often used in photonics because its characteristic length scale can be of the order of the wavelength of light. For example, a hyperswollen lamellar phase composed of bilayer membranes reflects visible light by the Br...

Gururaj-Rao, A.N.rasinga-Rao, M., 1983: Denaturation of the high molecular weight protein fraction of mustard (Brassica juncea) and rapeseed (Brassica campestris) by urea or guanidinium hydrochloride. Journal of biosciences 5(4): 311-320

Schuster, E.; Dunn-Coleman, N.; Frisvad, J.C.; Van Dijck, P.W.M., 2002: On the safety of Aspergillus niger--a review. Aspergillus niger is one of the most important microorganisms used in biotechnology. It has been in use already for many decades to produce extracellular (food) enzymes and citric acid. In fact, citric acid and many A. niger enzymes are considered...

Zimbric, M.G.; Chen, C.M.; Dikkeboom, A.L.; Jaeggi, J.J.; Johnson, M.E.; Tricomi, W.A., 1998: Manufacturing skim milk mozzarella cheese. Journal of Dairy Science 81(SUPPL 1): 31

Sutton, A., 1967: Reduction of strontium absorption in man by the addition of alginate to the diet. Nature 216(5119): 1005-1007

Floch, H., 1954: Mitsuda reaction, vaccination B.C.G. And leprosy immunity. Publication. Cayenne, French Guiana. Institut Pasteur de la Guyane Francaise et de L'inini 15(342): 1-4

Anonymous, 1955: ENDOMETRIAL biopsy. Cancer Bulletin 7(2): 38-40

Rezzola, S.; Nawaz, I.M.; Cancarini, A.; Ravelli, C.; Calza, S.; Semeraro, F.; Presta, M., 2017: 3D endothelial cell spheroid/human vitreous humor assay for the characterization of anti-angiogenic inhibitors for the treatment of proliferative diabetic retinopathy. Proliferative diabetic retinopathy (PDR) represents a main cause of acquired blindness. Despite the recognition of the key role exerted by vascular endothelial growth factor (VEGF) in the pathogenesis of PDR, limitations to anti-VEGF therapies do...

Lalande, S.; Johnson, B.D., 2008: Diastolic dysfunction: a link between hypertension and heart failure. Diastolic heart failure is characterized by the symptoms and signs of heart failure, a preserved ejection fraction and abnormal left ventricular (LV) diastolic function caused by a decreased LV compliance and relaxation. The signs and symptoms of...

Petrenko, A.G.; Krasnoperov, V.G., 2003: Nucleic acids encoding a calcium independent receptor of alpha-latrotoxin, characterization and uses thereof. A novel receptor of alpha-latrotoxin (alpha-LTx) which binds alpha-LTx independently of calcium (Ca2+) presence and is thus a mediator of the calcium-independent stimulation of neurotransmitter release by alpha-latrotoxin has been isolated, purifi...