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Improved liver function and decreased hepatitis C viral load after tacrolimus was replaced by cyclosporine


, : Improved liver function and decreased hepatitis C viral load after tacrolimus was replaced by cyclosporine. Transplantation Proceedings 37(6): 2871-2872

Potential antiviral properties of cyclosporine against hepatitis C virus have been highlighted in several publications. Therefore, we investigated the effect of a switch from tacrolimus to cyclosporine in a liver transplant recipient with recurrent hepatitis C who did not respond to antiviral therapy. The patient received a liver transplant for hepatitis C cirrhosis. Initial immunosuppressive treatment was based on tacrolimus. Because of viral activity, a combined therapy was initiated 20 months later including interferon and ribavirine. Then, due to a lack of virological and biochemical response, tacrolimus was replaced by cyclosporine (Neoral), while maintaining the same antiviral therapy. Decreases in the viral load and transaminases levels were observed.

US$19.90

PMID: 16182838

DOI: 10.1016/j.transproceed.2005.05.019


Other references

Lambertsen, R.H.; Weiss, L., 1983: Studies on the organization and regeneration of bone marrow: origin, growth, and differentiation of endocloned hematopoietic colonies. Hematopoietic colonies were studied by light microscopy in the marrow of alternate fraction x-irradiated mice (C576J/B1) to investigate the microenvironmental organization of marrow and identify early hematopoietic cell-stromal cell interactions....

Clausen, Curtis P., 1931: Biological notes on the Trigonalidae. Oviposition is upon the edges of leaves. Poecilogonalos maga* deposits on Rubus palmatus* and on red clover in Japan, sometimes up to 3600 eggs. Individuals of P. thwaitesii deposited up to 10,641 eggs in 14 days, and of P. henicospili, 5782 eggs...

Ruthirago, D.; Julayanont, P.; Tantrachoti, P.; Kim, J.; Nugent, K., 2016: Cardiac Arrhythmias and Abnormal Electrocardiograms After Acute Stroke. Cardiac arrhythmias and electrocardiogram (ECG) abnormalities occur frequently but are often underrecognized after strokes. Acute ischemic and hemorrhagic strokes in some particular area of brain can disrupt central autonomic control of the heart,...

Kytridis, V-Phaedon.; Karageorgou, P.; Levizou, E.; Manetas, Y., 2007: Intra-species variation in transient accumulation of leaf anthocyanins in Cistus creticus during winter: evidence that anthocyanins may compensate for an inherent photosynthetic and photoprotective inferiority of the red-leaf phenotype. Leaf color in some individuals of Cistus creticus turns transiently to red during winter, while neighboring individuals occupying the same site remain green. We have examined whether anthocyanin accumulation can be associated with variations in ph...

England, M.J., 1999: Capturing mental health cost offsets. Health Affairs 18(2): 91-93

Benassi, M.S.; Gamberi, G.; Ragazzini, P.; Sollazzo, M.R.; Ferrari, C.; Sangiorgi, L.; Treré, D.; Derenzini, M.; Picci, P., 1995: Bone hemangioendothelioma: an immunohistochemical study related to histological malignancy and proliferative activity (NORs). Aims and background: Forty-four bone hemangioendotheliomas (HEs) of different histological grades were studied to evaluate the expression and distribution of laminin, type IV collagen, cathepsin G and cathepsin D in cell differentiation and malign...

Becalski, A.; Bartlett, K.H., 2006: Methanol exposure to car occupants from windshield washing fluid: a pilot study. Automobile occupants might be exposed to considerable amounts of methanol from previously unreported source, namely via the inhalation of vapors of winter-grade, methanol-based, windshield washing fluid that drains to the intake air ducts of the c...

Schalekova, A.; Bystricka, H., 1956: Die Entwicklung des Palaogens in der kleinen Donauebene. Geologicky Sbornik Slovensk Akad Vied Bratislava, 7: 74-79

Glynn, D.; Gibson, H.E.; Harte, M.K.; Reim, K.; Jones, S.; Reynolds, G.P.; Morton, A.Jennifer., 2010: Clorgyline-mediated reversal of neurological deficits in a Complexin 2 knockout mouse. Complexin 2 is a protein modulator of neurotransmitter release that is downregulated in humans suffering from depression, animal models of depression and neurological disorders such as Huntington's disease in which depression is a major sympt...

Ugai, T.; Kanda, Y.; Morishima, Y.; Matsuo, K., 2017: Role of Genetic Polymorphism of ALDH2 in Hematopoietic Stem Cell Transplantation. Aldehyde dehydrogenase 2 (ALDH2) is involved in critically important biological processes, such as the metabolism of aldehydes and aldehyde-induced genotoxicity in hematopoietic stem cells. Given its role in these biological processes, we hypothes...