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Induction of antigen-specific regulatory T cell and its effect on the formation of atherosclerotic plaque


, : Induction of antigen-specific regulatory T cell and its effect on the formation of atherosclerotic plaque. Zhonghua Weishengwuxue He Mianyixue Zazhi 26(9): 795-799

Objective To explore the induction of antigen-specific-CD4(+) CD25(+) T cell in vitro and its effect on the formation of atherosclerotic plaque. Methods Immature dendrific cells were extracted and induced from apoE(-/-) mouse bone marrow and then used to induce heat shock protein 60-specific-CD4(+) CD25(+) T cells in vitro, the frequency of CD4(+) CD25(+) T cells and II-10 and TGF-beta 1 levels in the medium were analysed.

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