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John Biggins (1936-2004): his ingenuity, tenacity and humor; no-nonsense science with a big heart


, : John Biggins (1936-2004): his ingenuity, tenacity and humor; no-nonsense science with a big heart. Photosynthesis Research 85(3): 261-265

Topoisomerase II (Topo II) is a major component of mitotic chromosomes and its unique decatenating activity has been implicated in many aspects of chromosome dynamics including DNA replication, transcription, recombination, chromosome condensation and segregation. Of these, chromosome segregation is the most seriously affected by loss of Topo II, most probably because of residual catenations between sister chromatids.

US$19.90

PMID: 16170630

DOI: 10.1007/s11120-005-6313-3


Other references

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Kuriyama, A.; Watanabe, K.; Yamana, M., 2000: Effect of glycine and leucine on the recovery of frozen-thawed Lavandula vera cells. Ammonium ion is known to inhibit the recovery of frozen-thawed Lavandula vera [L. angustifolia] cells from freezing injury. In this study, we examined the effect of glycine and leucine on the recovery of frozen-thawed L. vera cells. Both amino aci...

Spivak, M.Ia.; Poliakova, A.K., 1967: A case of diabetes mellitus in association with diabetes insipidus. Terapevticheskii Arkhiv 39(2): 60-61

Beecher, H.A.; Caldwell, B.A.; DeMond, S.B.ett; Seiler, D.; Boessow, S.N., 2010: An Empirical Assessment of PHABSIM Using Long-Term Monitoring of Coho Salmon Smolt Production in Bingham Creek, Washington. We conducted a PHABSIM study on Bingham Creek, Washington, by using validated habitat suitability criteria for the rearing of coho salmon Oncorhynchus kisutch. We compared the relationship between weighted usable area (WUA) and flow with a previou...

Möbius, P.; Lentzsch, P.; Moser, I.; Naumann, L.; Martin, G.; Köhler, H., 2006: Comparative macrorestriction and RFLP analysis of Mycobacterium avium subsp. avium and Mycobacterium avium subsp. hominissuis isolates from man, pig, and cattle. In Germany, tuberculous lesions in slaughtered pigs due to infection with members of the Mycobacterium avium complex are increasingly reported. Contaminated food originating from pig or other livestock is discussed as potential source of human inf...

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Franceschini, M.; Baratta, S.; Zampolini, M.; Loria, D.; Lotta, S., 1997: Reciprocating gait orthoses: A multicenter study of their use by spinal cord injured patients. Objective: Use of reciprocating orthosis (RGO, ARGO, HGO) by 74 patients with complete traumatic spinal cord injury was studied. Lesion levels ranged from T1 to T12. Study Design: Patients were enrolled in seven Italian rehabilitation centers an a...

Wang, G-ying.; Yang, Y.; Zhang, Q.; Li, H.; Chen, G-zhong.; Yi, S-hong.; Xu, C.; Wang, G-shu.; Zhang, J.; Yi, H-min.; Jiang, N.; Fu, B-sheng.; Zhao, H.; Li, M-ru.; Chen, Y-hua.; Cai, C-jie.; Lu, M-qiang.; Chen, G-hua., 2012: Preoperative neutrophil-lymphocyte ratio as a prognostic predictor after liver transplantation for hepatocellular carcinoma. To analyze the negative impact of preoperative neutrophil-lymphocyte ratio (NLR) on the tumor recurrence of hepatocellular carcinoma (HCC) after orthotopic liver transplantation. The clinical data of HBV (hepatitis B virus)-associated HCC patients...

Leroy, T.; Montagnon, C.; Cilas, C.; Yapo, A.; Charmetant, P.; Eskes, A.B., 1997: Reciprocal recurrent selection applied to Coffea canephora Pierre. III. Genetic gains and results of first cycle intergroup crosses. Breeding of the allogamous C. canephora species in Cote d'Ivoire was based, from 1984 onward, on a reciprocal recurrent selection scheme exploiting the good performance of crosses between two genetically distinct populations (Guinean and Cong...

Romeo, F., 1951: Central nervous syndrome in pernicious anaemia and vitamin B12. The article is a review introducing a single case of pernicious anaemia in which loss of control of the lower limbs developed under liver-extract treatment which had maintained the blood picture fairly well. After injection of a total of 75 micro...