+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets

, : Kaiso/p120-catenin and TCF/beta-catenin complexes coordinately regulate canonical Wnt gene targets. Developmental Cell 8(6): 843-854

beta-catenin-dependent or canonical Writ signals are fundamental in animal development and tumor progression. Using Xenopus laevis, we report that the BTB/POZ zinc finger family member Kalso directly represses canonical Writ gene targets (Siamois, c-Fos, Cyclin-D1, and c-Myc) in conjunction with TCF/LEF (TCF). Analogous to P-catenin relief of TCF repressive activity, we show that p120-catenin relieves Kaiso-mediated repression of Siamois.


PMID: 15935774

DOI: 10.1016/j.devcel.2005.04.010

Other references

Thibaud, J-M.; Najt, J.; Jaquemart, S., 1994: Les collemboles (Insecta) de l'archipel des Galapagos 2. Isotomidae. We record in Galapagos Island 12 species of Collembola Isotomidae of which two are new: Folsomides delamarei n. sp. et Psammisotoma galapagoensis n. sp.

Reece, R.L.; Pass, D.A., 1986: Inclusion body pancreatitis in guinea fowl (Numida meleagris). During an outbreak of flaccid paralysis due to salinomycin poisoning in guinea fowl aged 3-4 weeks, three birds weighing only a quarter of their flock mates were submitted for histological examination. Each pancreas contained numerous foci of necr...

Petrocelli, J.V.; Glaser, B.A.; Calhoun, G.B.; Campbell, L.F., 2002: Early maladaptive schemas of personality disorder subtypes. This investigation attempted to examine the cognitive schemas of five distinct clusters that emerged from a cluster analysis of the personality disorder scales of the Millon Clinical Multiaxial Inventory-II (Millon, 1987). Specifically, the degree...

Beck, B.; Beck, J.; Kondla, N.; Bird, C.; Depeel, M.; Dockrill, C.; Drummond, P.; Girvan, L.; Eadie, G.; Fisher, C.; Hervieux, M.; Maccallum, B.; Manchak, J.; Mcphee, J.; Mcpike, S.; Mozak, L.; Pankratz, B.; Pankratz, H.; Peterson, G.; Smith, T.; Snyder, M.; Sperling, F.; Vanhala, S., 2004: 2003 Alberta butterfly counts. Nature Alberta 34(3): 1A-20A (Supplement)

Imamura, R.; Murakami, K., 1974: Laboratory study of mechanical pulping of sugar cane bagasse. To ascertain at what stage bagasse fibres were suitable for paper-making.

Mazyad, M.A.; Mostafa, M.M.; Morsy, T.A., 2003: Spinal cord schistosomiasis and neurologic complications. Affection of the spinal cord with schistosome eggs, although rare but do occur, causing many neurologic complications. The resulting mass may give rise to controversy in diagnosis. This can be more or less easily judged by MRI. However, radical su...

Katsuyama, Y.; Kita, T.; Horinouchi, S., 2009: Identification and characterization of multiple curcumin synthases from the herb Curcuma longa. Curcuminoids are pharmaceutically important compounds isolated from the herb Curcuma longa. Two additional type III polyketide synthases, named CURS2 and CURS3, that are capable of curcuminoid synthesis were identified and characterized. In vitro...

Huang, Z.; Sun, J., 2015: Development of Targets for Anti-influenza Virus Based on Nucleoprotein. The influenza A is an acute respiratory infection persistently threatening human health and social stability, and has caused high morbidity and mortality. The development of novel anti-influenza drugs based on new targets is very significant becau...

Marquant B.; Guienne L., 1991: In vitro fertilization ivf in bovine. Recueil de Medecine Veterinaire de l'Ecole d'Alfort 167(3-4): 303-312

Newmark, S.R.; Himathongkam, T.; Shane, J.M., 1975: Hyperglycemic and hypoglycemic crises. JAMA 231(2): 185-187