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Microarray analysis of IFN-gamma response genes in astrocytes

, : Microarray analysis of IFN-gamma response genes in astrocytes. Journal of Neuroimmunology 175(1-2): 19-30

IFN-gamma (IFN-gamma) has been shown to activate astrocytes to acquire immune functions. In this study the effect of IFN-gamma on murine astrocytes was investigated via microarray analysis. The activating effect of IFN-gamma on the astrocyte transcriptome showed predominance toward pathways involved in adaptive immunity, initiation of the immune response and innate immunity.


PMID: 16631260

DOI: 10.1016/j.jneuroim.2006.02.015

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