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NNC 55-0396 ((1S, 2S)-2-(2-(N-((3-benzimidazol-2-yl) propyl)-N-methylamino)ethyl)-6-fluoro-1,2,3,4- tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride): A new selective inhibitor of T- type calcium channels


, : NNC 55-0396 ((1S, 2S)-2-(2-(N-((3-benzimidazol-2-yl) propyl)-N-methylamino)ethyl)-6-fluoro-1,2,3,4- tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride): A new selective inhibitor of T- type calcium channels. Journal of Pharmacology and Experimental Therapeutics 309(1): 193-199

Mibefradil is a Ca2+ channel antagonist that inhibits both T-type and high-voltage-activated Ca2+ channels. We previously showed that block of high-voltage-activated channels by mibefradil occurs through the production of an active metabolite by intracellular hydrolysis.

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Pinsky, H.M.; Le, J.M.; Sweier, D.G.; Marti, K., 2016: Dental students' ability to locate emergency equipment-lessons learned from aviation. The purpose of this study was to evaluate the dental student's ability to locate medical emergency equipment/items at the University of Michigan School of Dentistry clinic. A total of 138 second-year dental students (traditional group) partic...

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