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Netrin-1 as a guidance molecule in the postnatal rat cochlea


, : Netrin-1 as a guidance molecule in the postnatal rat cochlea. Hearing Research 199(1-2): 117-123

During synaptogenesis a number of growth factors and peptides control the guidance of auditory neuron (spiral ganglion neuron, SGN) axons to their target cells. Furthermore, evidence suggests that these factors exert their actions at discrete times and sites during development. This study demonstrates that the guidance molecule netrin-1 is expressed in the early postnatal rat cochlea, but shows decreasing expression with increasing age. These results suggest that netrin-1 may be involved in guiding axonal growth from SGNs for the onset of innervation, but is not required for maintenance of synaptic connections. Copyright 2004 Elsevier B.V. All rights reserved.

US$19.90

PMID: 15574306

DOI: 10.1016/j.heares.2004.07.004


Other references

Dent, R.G.; Godden, D.J.; Stovin, P.G.; Stark, J.E., 1983: Pulmonary hyalinising granuloma in association with retroperitoneal fibrosis. Thorax 38(12): 955-956

Chrysochou, C.; Buckley, D.L.; Kalra, P.A., 2008: Magnetic resonance imaging: advances in the investigation of atheromatous renovascular disease. Prediction of renal functional outcome following revascularization procedures in atheromatous renovascular disease (ARVD) has remained a challenge. In considering the etiology of renal impairment, researchers have shifted their focus now from the...

Yamada M.; Djamgoz M.B.A.; Low J.C.; Furukawa T.; Yasui S., 1992: Dynamic characteristics of multiple cone synaptic input to h1 horizontal cells in carp retina in vitro. Journal of Physiology (Cambridge) 446: 375P

Weijers, R.N.M., 2014: Comment on Sprouse et al. SLC30A8 nonsynonymous variant is associated with recovery following exercise and skeletal muscle size and strength. Diabetes 2014;63:363-368. Diabetes 63(5): E8-E8

Chiappinelli, V.A.; Wolf, K.M., 1989: Kappa-neurotoxins: heterodimer formation between different neuronal nicotinic receptor antagonists. The kappa-neurotoxins are a family of snake venom polypeptides that are competitive antagonists of acetylcholine at a variety of neuronal nicotinic receptors. We have previously determined that kappa-bungarotoxin, purified from the venom of Bungar...

Vosta, J.; Kolar, J.; Klouda, M.; Petru, M., 1961: Our experience with modern anthelmintics. III. Therapy of the infestation with the tapeworm Hymenolepis nana with "Cestodin" and its comparison with Acranil. Casopis Lekaru Ceskych 100: 1169-1171

Crooks, G.E., 2002: Entropy production fluctuation theorem and the nonequilibrium work relation for free energy differences. There are only a very few known relations in statistical dynamics that are valid for systems driven arbitrarily far-from-equilibrium. One of these is the fluctuation theorem, which places conditions on the entropy production probability distributi...

Vashchenok, V.S., 2006: Species composition, host association and niche differentiation in fleas of small mammals in the Ilmen-Volkhov lowland. Species composition, abundance, annual cycles, and host association of fleas parasitizing small mammals were investigated. The problem of niche differentiation in these insects is considered on the base of the comparative analysis of their annual...

Anonymous, 1935: Section On Education (Q). Science 82(2117): 87-88

Huang Xuedong, 1990: Ranking technique and its application in ranking evaluation of geochemical anomaly from Hetai gold ore field. Guangdong Geology 5(2): 65-71