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Pathways involved in sunburn cell formation: deregulation in skin cancer


, : Pathways involved in sunburn cell formation: deregulation in skin cancer. Photochemical & Photobiological Sciences 5(2): 199-207

The incidence of squamous cell carcinoma of the skin is rising worldwide for decades. Chronic exposure to sunlight is the most important environmental risk factor for this type of skin cancer. This is predominantly due to the DNA damaging effect of ultraviolet-B (UVB) in sunlight. UVB induces also sunburn cells, i.e. apoptotic keratinocytes, which is a crucial protective mechanism against the carcinogenic effects of UVB irradiation.

US$19.90

PMID: 16465306

DOI: 10.1039/b504970a


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