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Pooling samples within microarray studies: a comparative analysis of rat liver transcription response to prototypical toxicants

, : Pooling samples within microarray studies: a comparative analysis of rat liver transcription response to prototypical toxicants. Physiological Genomics 22(3): 346-355

Combining or pooling individual samples when carrying out transcript profiling using microarrays is a fairly common means to reduce both the cost and complexity of data analysis. However, pooling does not allow for statistical comparison of changes between samples and can result in a loss of information.


PMID: 15914576

DOI: 10.1152/physiolgenomics.00260.2004

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