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Preferential mammary carcinogenic effects of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human c-Ha-ras proto-oncogene transgenic rats

, : Preferential mammary carcinogenic effects of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP) in human c-Ha-ras proto-oncogene transgenic rats. Cancer Science 95(5): 399-403

In order to clarify the susceptibility of the Hras128 rat harboring copies of the human c-Ha-ras proto-oncogene to 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), Hras128 rats were intragastically treated with 100 mg/kg PhIP 8 times (females) or 80 mg/kg PhIP 10 times (males) over a 9-week period, then sacrificed at weeks 12 and 30.


Other references

Y.S.; Trieu V.; Stiers D.L.; Mcconathy W.J., 1987: Interaction of human plasma lpa with other apolipoprotein b containing lipoproteins. Arteriosclerosis 7(5): 493A

Conill Serra, V., 1950: Can "mülleroma" be considered in the genesis of some forms of dysmenorrhea?. Obstetricia Y Ginecologia Latino-Americanas 8(3-4): 90-95

McElwain, J.C.; Punyasena, S.W., 2007: Mass extinction events and the plant fossil record. Five mass extinction events have punctuated the geological record of marine invertebrate life. They are characterized by faunal extinction rates and magnitudes that far exceed those observed elsewhere in the geological record. Despite compelling e...

Sengupta, R.; Witek, J.A.; Weinreb, S.M., 2011: Stereochemical investigation of conjugate additions of carbon- and heteronucleophiles to ring-substituted nitrosocyclohexenes. Intermolecular Michael-type conjugate additions of some in situ-generated ring-substituted nitrosocyclohexenes with both carbon- and heteronucleophiles have been found to be highly stereoselective, leading predominantly (or exclusively) to product...

Schwartzfarb L.; Needle M.; Chavez Chase M., 1974: Dose related inhibition of leukocyte migration by marihuana and delta 9 tetra hydro cannabinol in vitro. Journal of Clinical Pharmacology 14(1): 35-41

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Chirananthavat, T.; Tangsanga, K.; Eiam Ong, S., 1999: The applicability of hourly sampling of dialysate by modified direct dialysate quantitative method to approximating Kt/V, compare to total collection of dialysate. Journal of the American Society of Nephrology 10(PROGRAM AND ABSTR ISSUE): 327A, Sept

Boldireva, N.V., 1958: Differences in distribution of radioactive phosphorus in the muscles of healthy chickens infected with Syngamus. Papers on Helminthology presented to K I Skrjabin on his 80th Birthday Moscow : 86-88

Demeure, Micheal J., 1993: Physiology of the APUD system. The characteristic biochemical pathway of the APUDoma cell, namely amine precursor uptake and decarboxylation, are illustrated by the examples of serotonin and catecholamine metabolism. Increasing understanding of the origins of APUDomas as well a...

Flück, C.E.; Slotboom, J.; Nuoffer, J-Marc.; Kreis, R.; Boesch, C.; Mullis, P.E., 2003: Normal hepatic glycogen storage after fasting and feeding in children and adolescents with type 1 diabetes. Hypoglycemia is the most important acute complication in patients with type 1 diabetes. Liver glycogen is an important storage form of glucose and thus important for maintaining glucose homeostasis. To test the hypothesis whether abnormal storage...