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Rat brain proteome in morphine dependence

, : Rat brain proteome in morphine dependence. Neurochemistry International 49(4): 401-406

The aim of this study was to reveal potential markers associated with drug dependence, using the proteornic approach. Gels containing samples derived from morphine-treated and control animals were compared and analyzed. Inspection of protein profiles, following TCA/acetone precipitation and the use of nano-scale liquid chromatography coupled to tandem mass spectrometry, allowed for identification of eleven potential dependence markers, mainly cytoplasmic and mitochondrial enzymes, e.g. proteins that belong to GTPase and GST superfamilies, ATPase, asparaginase or proteasome subunit p27 families. (c) 2006 Elsevier Ltd. All rights reserved.


PMID: 16581157

DOI: 10.1016/j.neuint.2006.01.024

Other references

Friend, D.A., 1980: The ecology of amsinckia (Amsinckia spp.) in wheat crops in Victoria. The work reported is contained in a Ph.D. thesis submitted at the University of Melbourne in 1978. Amsinckia hispida, A. lycopsoides and A. intermedia are serious annual weeds of wheat in Victoria. The most widespread species, A. hispida, was used...

Balachowsky, A.S., 1952: Coccoidea-Diaspidinae nouveaux de Guinee FranYaise (A.O.F.). Revue de Pathologie Vegetale et d'Entomologie Agricole de France Paris, 31: 121-132

Ohnishi, K.; Ota, I.; Takahashi, A.; Yane, K.; Matsumoto, H.; Ohnishi, T., 2002: Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck. The present study examined whether X-ray- and CDDP-sensitivities depend on p53 gene status in human squamous cell carcinoma of the head and neck (SAS cells) showing dominant negative nature of mutant p53 protein. SAS cells were transfected with a...

Tyler A.V., 1969: Inst computer programs for analysis of feeding heterogeneities related to predator body size. Fisheries Research Board of Canada Technical Report 121: 1-49

Hunt L.A., 1982: Lectin affinity chromatography of sindbis virus and rous sarcoma virus glyco peptides and oligo saccharides. Glycopeptides and endoglycosidase-digested oligosaccharides from [3H]mannose-labeled Rous sarcoma virus and Sindbis virus were fractionated by lentil lectin-Sepharose and concanavalin A[ConA]-agarose affinity chromatography and subsequently analyz...

Demilo, A.B.; WarthenJ.D.vid, J.; Leonhardt, B.A., 1994: Capillary gas chromatography method for the analysis of the trans isomers of ceralure, a medfly attractant. A capillary GC method has been developed to analyze laboratory or commercial samples of the medfly attractant ceralure [ethyl 4- (and 5-)iodo-trans-2-methylcyclohexane-1-carboxylate]. The method utilizes a specially prepared fused-silica column wi...

Solorzano, Alejandro., 1995: Una nueva especie de serpiente venenosa terrestre del genero Porthidium (Serpentes: Viperidae), del Suroeste de Costa Rica. Revista de Biologia Tropical. 1994( ) Diciembre; 423: 695-701

Azimova, K.; Rude, J.; Mallawaarachchi, I.; Dwivedi, A.; Sarosiek, J.; Mukherjee, D., 2015: Glucose levels and depression in Hispanic patients admitted to the cardiovascular intensive care unit: a cross-sectional study. Depression is frequently associated with diabetes mellitus (DM) and may worsen DM-related morbidity and mortality. We determined the potential association of glucose levels with depression in Hispanic patients admitted to the Cardiovascular Intens...

Taguchi, H.; Kashii, S.; Kikuchi, M.; Yasuyoshi, H.; Honda, Y., 2000: Superior oblique paresis with contralateral relative afferent pupillary defect. Background: The purpose of this study is to report a case of superior oblique paresis and contralateral relative afferent pupillary defect (RAPD) with normal vision in a patient with brainstem astrocytoma. Methods: We correlated the patient's...

Johnson, J.A.; Willis, W.T.; Dallman, P.R.; Brooks, G.A., 1990: Muscle mitochondrial ultrastructure in exercise-trained iron-deficient rats. To investigate effects of endurance training and iron deficiency, as well as the combination of these two conditions, on mitochondrial ultrastructure, weanling rats at 3 wk of age were assigned to iron-deficient (Fe-) and iron-sufficient (Fe+) gro...