+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Retrospective evaluation of commonly used equations to predict energy expenditure in mechanically ventilated, critically ill patients

, : Retrospective evaluation of commonly used equations to predict energy expenditure in mechanically ventilated, critically ill patients. PharmacoTherapy 24(12): 1659-1667

Study Objective. To determine which of four commonly used equations to estimate energy expenditure is precise and unbiased compared with energy expenditure as measured by indirect calorimetry. Design. Retrospective, observational study. Setting. Adult medical intensive care unit in a research hospital of the National Institutes of Health Clinical Center. Patients. Seventy-six adult, mechanically ventilated, critically ill patients. Intervention. Indirect calorimetry reports generated by the National Institutes of Health Critical Care Medicine Department's Metabolic Cart Consult Service were reviewed. Bias and precision of resting energy expenditure (REE) estimated by equations were computed using mean prediction error (ME) and root mean squared prediction error (MSE). Equations were considered precise if the 95% confidence interval for MSE was within 15% of the measured energy expenditure (MEE) determined by indirect calorimetry. Equations were considered unbiased if the 95% confidence interval for ME included zero. Paired t tests were used to compare estimated REE values for each predictive equation with MEE values determined by indirect calorimetry. Data were stratified into regions of bias using classification and regression tree analysis, as well as visual inspection of estimated REE-versus-MEE curves for each equation. Measurements and Main Results. The Harris-Benedict equation multiplied by an activity factor of 1.2 was unbiased and precise. The Ireton-Jones equation was precise but biased. The American College of Chest Physicians' consensus recommendation was biased and imprecise. The Harris-Benedict equation without an activity factor also demonstrated bias and imprecision. Conclusions. The Harris-Benedict equation multiplied by an activity factor of 1.2 is suitable for predicting REE and may be used in the absence of indirect calorimetry.


PMID: 15585435

DOI: 10.1592/phco.24.17.1659.52342

Other references

Holm, T.; Moseley, R.D., 1964: The Conversion Factor For Image Intensifiers. Radiology 82: 898-904

Hartmann, P.; Mohokum, M.; Schlattmann, P., 2011: The association of Raynaud's syndrome with rheumatoid arthritis--a meta-analysis. Rheumatoid arthritis (RA) has traditionally been included among the diseases associated with Raynaud's syndrome (RS). The prevalence of RS in patients with RA is not well defined. The objective of this paper was to assess the prevalence of RS...

Poilleux, F.; Lievre, J.A.; Codron, P., 1957: Case of bone resorption caused by massive regional osteolysis. Memoires. Academie de Chirurgie 83(31-32): 966-73; Discussion 973-4

Holl, C.; Vykydal, S., 1961: The acclimatisation of Jersey cattle in Czechoslovakia. In 1956, twenty-three Jersey cows and pregnant heifers were imported from Denmark to the State Farm Stara Cervena Voda 320 m. above sea level with an av. temp. of 8.1 degrees C; in 1960 there were 133 purebred Jerseys. Data are given on the milk p...

Palmerini, E.; Bertoni, F.; Mercuri, M.; Barbieri, E.; Longhi, A.; Picci, P.; Bacci, G.; Ferrari, S., 2016: Six drugs induction chemotherapy for patients with localised Ewing sarcoma (ES): A pilot study. NlmCategory="UNASSIGNED">9537 Background: Vincristine (V), doxorubicin (A), cyclophosphamide (C), ifosfamide (I), actinomycin-D (Ac) and etoposide (E) are the standard drugs active against ES. Feasibility and efficacy of a six drugs i...

Ahlskog, J.E.; Kelly, P.J.; van Heerden, J.A.; Stoddard, S.L.; Tyce, G.M.; Windebank, A.J.; Bailey, P.A.; Bell, G.N.; Blexrud, M.D.; Carmichael, S.W., 1990: Adrenal medullary transplantation into the brain for treatment of Parkinson's disease: clinical outcome and neurochemical studies. Transplantation of adrenal medulla into the caudate nucleus as treatment for Parkinson's disease was performed in eight patients. Although our previous 6-month follow-up revealed early modest improvement, an extension of that follow-up to 1 y...

Pletnev S.D.; Abdurazakov M.Sh, 1976: Prospects for the use of gas continuous wave lasers in oncology. Sovetskaya Meditsina 8: 50-54

Lin, C-Jung.; Perng, W-Cherng.; Chen, C-Wen.; Lin, C-Kung.; Su, W-Lin.; Chian, C-Feng., 2009: Small cell lung cancer presenting as ectopic ACTH syndrome with hypothyroidism and hypogonadism. Small-cell lung cancer accounts for 15-20% of all lung cancers, and it is the cell type most commonly associated with paraneoplastic syndrome. Small-cell lung cancer presenting as ectopic adrenocorticotropic hormone (ACTH) syndrome associated with...

Demetrian, S., 1977: The striated muscles: general and functional anatomy. Soins; la Revue de Reference Infirmiere 22(23): 3-11

Buist P.H.; Marecak D.M., 1992: Stereochemical analysis of sulfoxides obtained by diverted desaturation. We have shown that the .delta.9-desaturase of Saccharomyces cerevisiae can behave as a regio- and enantioselective oxygenating agent. The stereochemistry of oxygenation matches that of hydrogen removal in the desaturation process. Thus methyl 9-th...