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Severe systemic hypersensitivity reaction to ibuprofen: A presentation of systemic lupus erythematosus


, : Severe systemic hypersensitivity reaction to ibuprofen: A presentation of systemic lupus erythematosus. Journal of Rheumatology 33(1): 171-172

We describe the first severe systemic hypersensitivity reaction to ibuprofen in a pediatric patient with previously undiagnosed systemic lupus erythematosus (SLE). An 11-year-old Thai male presented with fever, rash, altered mental status, and hypotension after oral administration of ibuprofen leading to the diagnosis of SLE. Re-dosing with ibuprofen resulted in recurrence of presenting symptoms.

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