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Sickle red cell microrheology and sickle blood rheology

, : Sickle red cell microrheology and sickle blood rheology. Microcirculation 11(2): 209-225

The hallmark of the phenotypic expression of sickle cell disease is the remarkable degree of heterogeneity in the clinical manifestations. They vary latitudinally among patients and longitudinally in the same patient. The pathogenesis of sickle cell anemia centers on the sequence of events that occur between polymerization of deoxy hemoglobin S and increased red cell destruction, vasoocclusion, and end organ damage. Cellular dehydration, changes in sickle red blood cell rheology, adhesion of sickle red cells to vascular endothelium, inflammatory response, and tissue injury are some of the factors that contribute to hemolytic anemia, vasoocclusion, and eventual multiorgan damage. The focus of this review is on the rheology of sickle blood and microrheology of sickle RBC. Determinants of sickle RBC rheology and the factors that modulate its severity are discussed.


PMID: 15280093

DOI: 10.1080/10739680490279410

Other references

Attar U.Rahman, 1971: Partial synthesis of delta 15 20 anhydro vinblastine. Pakistan Journal of Scientific & Industrial Research 14(6): 487-488

Bartter F.C., 1968: Hyper thyroidism and renal tubular acidosis human. Archives Of Internal Medicine: 118-122

Goddard, Hw, 1994: Being understanding: a key to developing healthy children. Circular HE 94 (682)

Ucar, Y.; Brantley, W.A.; Bhattiprolu, S.N.; Johnston, W.M.; McGlumphy, E.A., 2009: Characterization of cast-to implant components from five manufacturers. Cast-to components are commonly used in screw-retained implant-supported restorations to produce precise fit. There is little information in the literature about the compositions and microstructures of commercially available products. The purpose...

Babala, J., 1972: Histopathological changes of fetal adnexa in intrauterine dead fetuses. Ceskoslovenska Gynekologie 37(6): 403-404

Recchioni, R.M., 1954: Androstenediol derivatives in gynecology. Gazzetta Medica Italiana 113(6): 171-173

Rennie, P.S.; Snoek, R.; Bruchovsky, N.; Kasper, S.; Matusik, R.J.; Gleave, M.; Sato, N.; Mawji, N.R., 1997: Differential gene induction in prostate cancer cells by AF-1 and AF-2 of the androgen receptor. Clinical & Investigative Medicine 20(4 SUPPL ): S18

Money, J., 1974: Long-term psychologic follow-up of intersexed patients. Clinics in Plastic Surgery 1(2): 271-274

Davies, H.D.; Sakuls, P.; Keystone, J.S., 1993: A review of clinical presentation and management of 60 cases presenting to a tropical disease unit. Background and Design: Cutaneous larva migrans is an infection with a larval nematode, most frequently by dog or cat hookworms. It has a characteristic presentation that is easily recognizable. We reviewed the charts of 60 patients with cutaneous...

Vatta, M.; Jimenez, S.; Stetson, S.J.; Becker, K.; Towbin, J.A.; Torre Amione, G.; Bowles, N.E., 2003: Myocardial structural recovery is associated with apoptosis inactivation in biomechanical unloaded heart by LVAD therapy. Journal of Heart & Lung Transplantation 22(1S): S210, January