geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The construction of meaning in computational integrative biology


, : The construction of meaning in computational integrative biology. Omics 8(2): 95-105

It is the contention of this paper that current data mining work in bioinformatics tends to emphasize data representation to the neglect of another essential aspect of biological systems, namely dynamics. This results in a divorce of both the enterprise and the teaching of bioinformatics from its central aim of meaning-construction. The paper argues that this neglect of dynamics is rooted in an information-processing view of cognitive psychology, and needs to be complemented by a more narrative perspective which emphasizes the explanation, rather than the mere description, of observed patterns in data. This increased emphasis on explanatory narrative in the form of dynamical modeling leads to both a deeper understanding of biological information and a more invigorating approach to the teaching of bioinformatics. The paper presents a cross-curricular teaching framework for a first-year undergraduate course in bioinformatic dynamical modeling which is based around the use of narrative plots.

US$19.90

PMID: 15268769

DOI: 10.1089/1536231041388357


Other references

Dulla, O.; Jahan, F.Israt., 2017: Ethnopharmacological survey on traditional medicinal plants at Kalaroa Upazila, Satkhira District, Khulna Division, Bangladesh. The traditional source of medicinal plants is an important way for daily curative uses in the rural area throughout Bangladesh. An ethnomedicinal survey was conducted in a randomized manner among traditional medicinal practitioners to find out abo...

Janicki E.P., 2004: Hydrocarbon pools of the Colville Hills, Northwest Territories. CSPG Annual Convention 2004: (unpaginated

Harris, G.D.; Finseth, F.; Buncke, H.J., 1980: The hazard of cigarette smoking following digital replantation. Two case histories are presented in which cigarette smoking in the early postoperative period following digital replantation led to vasospasm and thus compromise of the microvascular anastomoses.

Gardner, C.; Nielsen, L.; Knight, K., 1973: Morphology of the mouthparts of larval Aedes communis (DeGeer): (Diptera: Culicidae). Mosquito systematics news letter: 5, 5 (2) 163-182

Serrao, E.A.; Teixeira, L.B.; Oliveria, R.F. de; Bastos, J.B., 1995: Soil alterations in perennial pasture and agroforestry systems in the Brazilian Amazon. Soil transformations in pasture, agroforestry and silvopastoral systems were studied in long-term soil management experiments in the Amazon. Information is presented on productivity, physical and chemical soil alterations in relation to current an...

Yang, F.E.; Nautiyal, J.; Powers, C.; Hallahan, D.; Vijayakumar, S.; Ultmann, J.E.; Weichselbaum, R.R., 1996: Reduction of adverse effects of combined modality therapy with subtotal nodal irradiation in stage IIIA Hodgkins disease. International Journal of Radiation Oncology Biology Physics 36(1 SUPPL ): 356

Wongsak, S.; Kawinwonggowit, V.; Mulpruck, P.; Channoom, T.; Woratanarat, P., 2010: Accuracy of knee implants sizing predicted by digital images. Accurate preoperative templating to predict implant size and position can facilitate precise, efficient, and reproducible knee replacement operations. Preoperative templating for total knee arthroplasty can be performed with digital images of the...

Taylor, S.S.; Buechler, J.A.; Yonemoto, W., 1990: cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes. cAPK has provided many insights into the functioning of the diverse family of eukaryotic protein kinases. The fact that a particular amino acid in the catalytic core is conserved is an indication that the residue plays an important role; however,...

Lang, T.; Coenen, H., 2000: Functional potentials of the rear three-point linkage. Since the invention of the three-point power lift, the basic mechanical principle applied has hardly changed. Automatic electronic control loops are available to increase the flexibility of kinematic and automation potentials. A concept presented...

Basore, J.R.; Lavrik, N.V.; Baker, L.A., 2010: Single-pore membranes gated by microelectromagnetic traps. Advanced Materials 22(25): 2759-2763