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The immune response to AIDS virus infection: good, bad, or both?

, : The immune response to AIDS virus infection: good, bad, or both?. Journal of Clinical Investigation 113(6): 808-810

A potent antigen-specific T cell response to HIV infection can contribute to the control of viral replication and is therefore beneficial to the host. However, HIV-mediated increases in generalized T cell activation also appear to accelerate both viral replication and CD4+ T cell depletion. A new study in the JCI attempts to experimentally distinguish the beneficial versus harmful aspects of this immune response.


PMID: 15067312

DOI: 10.1172/JCI21318

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