+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The immune response to parvovirus B19 exposure in previously seronegative and seropositive individuals

, : The immune response to parvovirus B19 exposure in previously seronegative and seropositive individuals. Journal of Infectious Diseases 194(2): 154-158

Little information is available on the immune response to parvovirus B19 after the administration of contaminated blood products. In the present study, we found that levels of B19 IgG in B19-seropositive recipients protect against reinfection and, after transfusion with pooled plasma containing B19 DNA (1.6 x 10(8) IU/mL), increase from 19-39 IU/mL to 50-100 IU/mL. We found that, in the presence of 1.6-2.2 x 10(8) IU of B19 DNA/mL in B19-seronegative recipients, a pooled-plasma B19 IgG level of 59.5 IU/mL is insufficient to prevent B19 transmission and subsequent seroconversion. These data should lead to improvements in the assessment of blood-product safety.


PMID: 16779720

DOI: 10.1086/505226

Other references

Jones, L.R.; Mabe, P.A.; Riley, W.T., 1989: Illness coping strategies and hypochondriacal traits among medical inpatients. The Illness Coping Strategies scale (ICS) is an 18-Likert-item scale developed to examine illness appraisal and coping by medical patients more comprehensively than instruments which screen for hypochondriacal traits in this population. This study...

Slepushkina, G.; Proshunina, M.; Kozlova, V., 1972: Biological and economic qualities of potato varieties. Trudy po prikladnoaei botanike genetike i seleketisii: 8 (2) 141-152

Starr, M., 1997: Erratum to "Theory and practice of myofascial pain as both practicing clinician and patient" (a Physician Commentary)[J. Back Musculoskeletal Rehabil. 8 (1997) 173. Journal of Back and Musculoskeletal Rehabilitation 8(3): 247-247

Siganos, D.S.; Papastergiou, G.I.; Moedas, C., 2004: Assessment of the Pascal dynamic contour tonometer in monitoring intraocular pressure in unoperated eyes and eyes after LASIK. To assess the performance of the Pascal dynamic contour tonometer (PDCT) (Swiss Microtechnology AG) by comparing it to Goldmann applanation tonometry (GAT) and noncontact air tonometry (NCT) before and after laser in situ keratomileusis (LASIK). V...

Smith, J.; Gatch, R.; Palm, K., 2003: Plant spacing accuracy of sugarbeet planter models and of options within planter models. Correct plant population and consistent spacing between plants are necessary to optimize sugarbeet yield, to minimize weed competition, and to minimize harvest loss. Selection, adjustment, and options of the sugarbeet planter influence plant popul...

Yang C.H.; Titchener E.B., 1976: Isolation and physical properties of a sulfur deficient phenyl alanine transfer rna from escherichia coli. Federation Proceedings 35(7): 586

Kiviluoto, M.; Räsänen, O.; Rinne, A.; Rissanen, M., 1979: Effects of vanadium on the upper respiratory tract of workers in a vanadium factory. A macroscopic and microscopic study. An epidemiologic cross-sectional case-history study on the injurious effects of vanadium was carried out among the workers of a vanadium factory. The upper respiratory tract of 63 male workers exposed to vanadium dust was examined macroscopically...

Lu, Y.; Li, L.; Luo, W., 2002: A study on the changes of calcium signal in mast cells activated by antigen. To study the relationship between the calcium signal and activation of mast cells, laying the foundation for discovering a new potential theraputical target of signal transduction for type I anaphylactic diseases like asthma. The fluorescent Ca2+...

Gwinner, W.; Plasger, J.; Brandes, R.P.; Kubat, B.; Schulze, M.; Regele, H.; Kerjaschki, D.; Olbricht, C.J.; Koch, K.M., 1998: Passive Heymann-nephritis Central pathophysiological role of xanthine oxidase. Journal of the American Society of Nephrology 9(PROGRAM AND ABSTR ISSUE): 610A-611A, Sept

Present, J.; Crits-Christoph, P.; Connolly Gibbons, M.Beth.; Hearon, B.; Ring-Kurtz, S.; Worley, M.; Gallop, R., 2007: Sudden gains in the treatment of generalized anxiety disorder. The objective of this study was to investigate the prevalence and timing of sudden gains over the course of brief, psychodynamically oriented treatment for generalized anxiety disorder (GAD). Data were used from two studies of brief (i.e., 16-sess...