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The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration


, : The immunogenicity of dendritic cell-based vaccines is not hampered by doxorubicin and melphalan administration. Journal of Immunology 174(6): 3317-3325

Immunization of cancer patients is most effective in tumor-free conditions or in the presence of minimal residual disease. In the attempt to develop new strategies able to control tumor recurrence while allowing the development of protective immunity, we have investigated the immunogenic potential of two distinct vaccine formulations when provided alone or upon single and repeated treatment with chemotherapeutics drugs.

US$19.90

PMID: 15749863

DOI: 10.4049/jimmunol.174.6.3317


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