+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The impact of behavioural changes on the prevalence of human immunodeficiency virus and hepatitis C among injecting drug users

, : The impact of behavioural changes on the prevalence of human immunodeficiency virus and hepatitis C among injecting drug users. International Journal of Epidemiology 32(5): 708-714

Background: Prevalence of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in the injecting drug user (IDU) community can differ considerably. In Australia in 1997, HIV prevalence among attendees at Needle Exchange Programs was 1% while HCV prevalence was 50%. The impact that different needle-sharing behaviour and drug injecting use may have on the future levels of these viruses is uncertain. Method: We develop a mathematical model of the number of people who inject drugs with each of these infections to determine their changes under different scenarios. The impact of transmission probabilities and needle sharing on the incidence and prevalence of HIV and HCV infections are assessed. Results: Critical levels of needle sharing, below which total infections would fall to minimal levels, were estimated to be 17 IDU partners per year for HIV compared with 3 IDU partners per year for HCV. Current average levels of needle sharing in Australia are estimated to be six IDU partners per year. Conclusions: This analysis suggests that under current drug injecting behaviour, HIV prevalence in IDU in Australia should remain below 1% but that HCV prevalence will stay elevated.


PMID: 14559736

DOI: 10.1093/ije/dyg102

Other references

Shannon, K., 1984: Hopes of earlier diagnosis spur research, despite costs. Hospitals 58(24): 68-69

Zhang, F.; Zhao, L.; Feng, X.; Hu, X., 2016: An Investigation on Self-Rated Health of Adolescent Students and Influencing Factors From Sichuan, China. To investigate adolescent students' self-rated health status and to identify the influencing factors that affect students' health status. A stratified cluster sampling method and the Self-assessed General Health Questionnaires were used...

Gerencser, G.A., 1988: Sodium and chloride transport across the molluscan gut. This review focuses on the author's own laboratory work on sodium and chloride transport across the intestine of Aplysia.

Rajput, A.M.; Saraf, G.P.; Dinesh Swarnkar; Jain, S.K., 2001: Impact of watershed technology in Indore district of Madhya Pradesh. The objectives of the present study were to calculate the cost:benefit ratio of the adoption of watershed technology and to evaluate the investment pattern and the benefits from adopting the technology. Samples of 2 two villages from a watershed a...

Milenković, I.; Witte, M.; Turecek, R.; Heinrich, M.; Reinert, T.; Rübsamen, R., 2007: Development of chloride-mediated inhibition in neurons of the anteroventral cochlear nucleus of gerbil (Meriones unguiculatus). At the initial stages in neuronal development, GABAergic and glycinergic neurotransmission exert depolarizing responses, assumed to be of importance for maturation, which in turn shift to hyperpolarizing in early postnatal life due to development...

Solomina, I.P., 1984: Storage of potatoes. Methods and construction of buildings for storage of potato tubers in different countries are briefly discussed.

Yolken, R.H.; Leister, F.J., 1981: Evaluation of enzyme immunoassays for the detection of human rotavirus. Journal of Infectious Diseases 144(4): 379-379

Kiernan, T.J.; Yan, B.P.; Ruggiero, N.; Eisenberg, J.D.; Bernal, J.; Cubeddu, R.J.; Witzke, C.; Don, C.; Cruz-Gonzalez, I.; Rosenfield, K.; Pomersantev, E.; Palacios, I., 2010: Coronary artery perforations in the contemporary interventional era. Coronary perforations represent a serious complication of percutaneous coronary intervention (PCI). We performed a retrospective analysis of documented coronary perforations at Massachusetts General Hospital from 2000 to 2008. Medical records revi...

Storek, J.; Lalovic, B.B.; Rupert, K.; Dawson, M.A.; Shen, D.D.; Maloney, D.G., 2001: Kinetics of B, CD4 T and CD8 T cells infused into humans Estimates of intravascular Extravascular ratios and total body counts. Little is known about the rate of T and B cell traffic from blood to extravascular compartments or about the steady-state distribution of T and B cells between intravascular and extravascular compartments in humans. We quantitated circulating T an...

Liu, S.; Chen, J-Fan., 2012: Strategies for therapeutic hypometabothermia. Although therapeutic hypothermia and metabolic suppression have shown robust neuroprotection in experimental brain ischemia, systemic complications have limited their use in treating acute stroke patients. The core temperature and basic metabolic...