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The impact of blood contamination on the proteome of cerebrospinal fluid

, : The impact of blood contamination on the proteome of cerebrospinal fluid. Proteomics 5(1): 290-296

Human cerebrospinal fluid (CSF) is in direct contact with the brain extracellular space. Beside the secretion of CSF by the choroid plexus the fluid also derives directly from the brain by the ependymal lining of the ventricular system and the glial membrane and from blood vessels in the arachnoid. Therefore, biochemical changes in the brain may be reflected in the CSF. CSF is a potential source of protein molecular indices of central nervous system function and pathology.


PMID: 15672452

DOI: 10.1002/pmic.200490084

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