+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The impact of genomics on discovering drugs against infectious diseases

, : The impact of genomics on discovering drugs against infectious diseases. Microbes and Infection 8(6): 1654-1661

Genomics is accelerating the progress in data generation and interpretation in the global analyses of components of cells, including the spectrum of lipids, RNA, metabolites, proteins, mutational phenotypes or DNA methylation sites. Integration of the knowledge generated by these diverse strategies is predicted to have a tremendous impact on approaches to rational drug discovery against infectious diseases. Published by Elsevier SAS.


PMID: 16690340

DOI: 10.1016/j.micinf.2005.11.018

Other references

Calvert, Philip P., 1926: The entomological work of Henry Skinner. A specialist in Rhopalocera, Skinner is best known as the editor of Entomological News 1890-1910. His early work was signed Harry Skinner.

Frank, R.M.; Romeo, A.A.; Bush-Joseph, C.A.; Bach, B.R., 2017: Injuries to the Female Athlete in 2017: Part II: Upper and Lower-Extremity Injuries. Jbjs Reviews 5(10): E5-E5

Caullery, M., 1956: Adaptation, genetique et evolution. Int Congr Zool. 1953( ); 14: 89-94

Charles Tortoe; Paa-Nii T.J.hnson; Apollonius I.N.arko, 2009: Effects of osmo-dehydration, blanching and semi-ripening on the viscoelastic, water activity and colorimetry properties of flour from three cultivars of plantain ( Musa AAB). Innovative Food Science & Emerging Technologies 10(1): 0-86

Rizzo, S.C.; Fratti, L.; Turba, G., 1962: Observations on the behavior of plasma-insulin-activity in obese type diabetes. The behavior of plasma-insulin activity has been studied in 2 groups of obese type diabetics, never treated and on insulin treatment, respectively, by means of the diaphragm test and by direct comparison with the plasma of normal subjects. Both gr...

Carpenter, G.D.H., 1947: The different kinds of protective coloration in insects and their interpretation. South Eastern Naturalist, 52: 34-41

Lhote, F.; Guillevin, L., 1996: Indications for plasma exchange in the treatment of polyarteritis nodosa, Churg-Strauss syndrome and other systemic vasculitides. Since 1977, plasma exchanges (PE) have been proposed to treat immune-mediated disease, especially when an immune complex-induced mechanism is suspected, including vasculitis and particularly polyarteritis nodosa (PAN) and Churg-Strauss syndrome (C...

Abraham, P.Francis., 2012: A case series of lamotrigine increased to 300mg daily in patients with bipolar depression. Bipolar depression is a condition lacking sufficient treatment options. While lamotrigine appears effective, clinical trials and prescribing guidelines address only daily doses below 300mg. Thirteen consecutive outpatients with bipolar depression...

Pedersen, O.L.; Mikkelsen, E.; Andersson, K.E., 1979: Comparison of the in vitro effects of prazosin, nifedipine, and dihydralazine in isolated human mesenteric and crural vessels. The inhibitory and relaxing effects of prazosin, nifedipine, and dihydralazine on contractions induced by noradrenaline (NA), or potassium (K+), were investigated in isolated human crural and mesenteric arteries and veins. Vascular ring preparatio...

L.P.Vidhana Arachchi, 2009: Effect of deep ploughing on the water status of highly and less compacted soils for coconut Cocos nucifera L production in Sri Lanka. Soil compaction limits soil water availability which adversely affects coconut production in Sri Lanka. Field experiments were conducted in coconut (Cocos nucifera L.) plantations with highly and less compacted soils in the intermediate climatic z...