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Tissue specificity of alternative splicing of transcripts encoding hampin, a new mouse protein homologous to the Drosophila MSL-1 protein


, : Tissue specificity of alternative splicing of transcripts encoding hampin, a new mouse protein homologous to the Drosophila MSL-1 protein. RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY 31(4): 325-331

A number of mammalian genomes have one gene copy encoding the protein that we named hampin. A search in a number of databases revealed a distant homologue, the well-known Drosophila protein MSL-1 (male-specific lethal 1). An alternative splicing of mRNA led to a significant diversity of structural hampin variants with different domain compositions. We analyzed the tissue-specific expression of five mouse hampin variants using RT-PCR.

US$19.90

DOI: 10.1007/s11171-005-0045-1


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