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Vacuolating cytotoxin of Helicobacter pylori

, : Vacuolating cytotoxin of Helicobacter pylori. Iranian Journal of Biotechnology 1(2): 73-81

Vacuolating cytotoxin (VacA) is one of the most important virulence factors of H. pylori (Hp), which is the only toxic protein that is secreted from Hp cell into the culture supernatant. The effects of VacA on eukaryotic systems is the subject of many previous and on going research studies. Intracellular targets for this toxin include: late endosomal and lysosomal compartments, mitochondria, cell-cell junctions and phospholipid bilayers.


Other references

Mimiaga, M.J.; Reisner, S.L.; Goldhammer, H.; Tetu, A.M.; Belanoff, C.; Mayer, K.H., 2010: Sources of human immunodeficiency virus and sexually transmitted disease information and responses to prevention messages among Massachusetts men who have sex with men. American Journal of Health Promotion 24(3): 170-177

Heo, K.; Min, S-Won.; Sung, H.Jin.; Kim, H.Gyul.; Kim, H.Jung.; Kim, Y.Hee.; Choi, B.Kyu.; Han, S.; Chung, S.; Lee, E.Sook.; Chung, J.; Kim, I-Hoo., 2016: An aptamer-antibody complex (oligobody) as a novel delivery platform for targeted cancer therapies. Aptamers have recently emerged as reliable and promising targeting agents in the field of biology. However, their therapeutic potential has yet to be completely assessed due to their poor pharmacokinetics for systemic administration. Here, we desc...

Saric R.; Stepanek P., 1997: The geology of menhirs in central and northwestern Bohemia. Vestnik Ceskeho Geologickeho Ustavu = Bulletin of the Czech Geological Survey 72(1): 15-26

Bobba, R.K.; Garg, P.; Arya, M.; Freter, C.E., 2011: Postoperative bleeding in an elderly patient from acquired factor V inhibitor: rapid response to immunosuppressive therapy. Acquired factor V inhibitor is a rare but potentially life-threatening hemorrhagic disorder caused by the development of autoantibodies directed against coagulation factor V. The management of acute bleeding and inhibitor eradication is the mainst...

Hauman, C.H.J.; Love, R.M., 2003: Biocompatibility of dental materials used in contemporary endodontic therapy: a review. Part 1. Intracanal drugs and substances. Irrigation solutions and intracanal medicaments are used within the root canal to clean and aid in disinfecting the dentinal walls. Although these materials are intended to be contained within the root canal, they invariably contact the periapical...

Pasic, M.; Carrel, T.; Laske, A.; Bauer, E.; Turina, J.; Jenni, R.; von Segesser, L.; Turina, M., 1992: Valve replacement in octogenarians: increased early mortality but good long-term result. Between January 1983 and December 1990, 20 patients aged 80 years or older underwent valvular surgery. The patients' ages varied from 80 to 87 years (mean, 82 +/- 1.5 years). The indication for operation was aortic stenosis in 19 patients, an...

Nataraj, A.J.; Black, H.S.; Ananthaswamy, H.N., 1996: P53 Mutation at DNA cross-linking sites in 8-methoxypsoralen and UV-A-induced skin cancers. Photochemistry & Photobiology 63(SPEC ISSUE): 55S-56S

Tring, F.C., 1977: Chilblains. Nursing Times 73(45): 1752-1753

Hill, D.A., 1992: Role of the pre-test in the progressive assessment of medical students. A prospective, randomized, controlled trial was conducted to see if a pre-test, given immediately before teaching, improved performance in a subsequent post-test. The study was also used to assess the educational value of a structured teaching met...

Seiler, HG., 1988: Analysis of nickel in biological materials. Metal Ions in Biological Systems, 23: 403-428