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Antioxidant activity of piper betel leaf extract and its constituents


, : Antioxidant activity of piper betel leaf extract and its constituents. Journal of Agricultural and Food Chemistry 54(24): 9046-9054

The 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay of the ethanol extracts of three varieties (Bangla, sweet, and Mysore) of Piper betel( pan) revealed the Bangla variety to possess the best antioxidant activity that can be correlated with the total phenolic content and reducing powers of the respective extracts. Column chromatography of the extract of the Bangla variety led to the isolation of chevibetol (CHV), allylpyrocatechol (APC), and their respective glucosides. The HPTLC analyses of the extracts revealed similar chemical profiles in all three P. betel varieties, although the concentrations of CHV and APC were significantly less in the sweet and Mysore varieties. Among the isolated compounds, APC showed the best results in all the in vitro experiments. It could prevent Fe(II)-induced lipid peroxidation (LPO) of liposomes and rat brain homogenates as well as gamma-ray-induced damage of pBR322 plasmid DNA more efficiently than CHV. The superior anti-LPO and radioprotective activities of APC vis-a-vis those of CHV could not be explained by their respective Fe(II) chelation and center dot OH radical scavenging capacities. The better ability of APC to scavenge O-2(-center dot) radicals and H2O2 might account for the results.

US$19.90

PMID: 17117789

DOI: 10.1021/jf061679e


Other references

Price M.R.; Edwards S.; Baldwin R.W., 1986: Application of a subcellular membrane antibody binding assay for the analysis of antigen expression in human tumors. A micro-radioisotopic antiglobulin assay has been employed to determine the binding of monoclonal antibodies to subcellular membranes adsorbed to the wells of Terasaki Microtest Plates. A panel of 15 monoclonal antibodies was tested against 22 mem...

Kato, M.; Inoue, T.; Nagamitsu, T., 1995: Pollination biology of Gnetum (Gnetaceae) in a lowland mixed dipterocarp forest in Sarawak. Pollination biology of two Gnetum species was studied in a lowland mixed dipterocarp forest in Sarawak, Malaysia. A dioecious shrub species, G. gnemon var. lenerum, flowered in the evening and its strobili emitted a stinking odor. Pollination drop...

Nanjundappa, D., 1957: A note on Eucalyptus plantations in old Mysore State. More than 5300 acres of Eucalypt (mainly E. citriodora) plantations have been established in Mysore. Some account is given of methods employed and costs of establishment.

V.C.M.lina; M.M.©dici; M.P.T.ranto; G.F.nt de Valdez, 2009: Lactobacillus reuteri CRL 1098 prevents side effects produced by a nutritional vitamin B12 deficiency. Journal of Applied Microbiology 106(2): 467-473

Anonymous, 1906: The Report Of The Income-Tax Committee. British Medical Journal 2(2397): 1643-1644

Udagawa, T., 1980: Canopy structure in crops and its models. Canopy structure was investigated using 3 methods in sunflower, wheat, barley, rape and 2 cv. of maize. Crop canopies were divided into those with max. density in the upper, middle or lower layers. Leaf area distributions were compared and the dis...

Anonymous, 2014: Pulmonary embolism after a single-stage, combined anterior and posterior approach lumbar surgery. Pulmonary embolism is a fatal complication in orthopaedics surgery. While, the incidence of this life-threatening condition is low in spine surgery and few detailed reports have been published in English literatures. We present a case of pulmonary...

Toker, L.; Pavlidis, P., 2015: Metaanalysis of flawed expression profiling data leading to erroneous Parkinson's biomarker identification. Proceedings of the National Academy of Sciences of the United States of America 112(28): E3637-E3637

Kara, K.; Ozturk, E.; Sildiroglu, O., 2016: Role of Coronary CT Angiography in Patients with Stroke. Radiology 278(3): 959-959

Yamaguchi, Keiko, 1994: Retinal transplantation A possible approach to retinal disorders. Nichidai Igaku Zasshi 53(5): 388-395