geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Isotopic criteria in the characterization of aromatic molecules. 1. Hydrogen affiliation in natural benzenoid/phenylpropanoid molecules


, : Isotopic criteria in the characterization of aromatic molecules. 1. Hydrogen affiliation in natural benzenoid/phenylpropanoid molecules. Journal of Agricultural and Food Chemistry 54(26): 10112-9

The site-specific isotope ratios of several families of aromatic molecules are analyzed in terms of hydrogen affiliation and discriminating potential. Among the aromatic molecules produced by plants, many are biosynthesized by the shikimate pathway, but the terpenic pathway also forms some compounds with a benzenic ring. In compounds of the phenylpropanoid family, specific hydrogen connections are determined with cinnamic acid, a key intermediate in the formation of a large number of aromatic molecules. Then affiliations through the phenylalanine precursor, back to the parent D-erythrose 4-phosphate and phosphoenolpyruvate molecules and finally to glucose, are considered. Typical isotopic profiles of the benzenic ring in natural, as compared to non-natural, molecules are defined. The dispersion observed in the (D/H)(i) ratios of the lateral chains is illustrative of diverse mechanistic responses and the role of exchange phenomena. The isotopic patterns of aromatic molecules pertaining to the terpenic family are drastically different from those of the shikimate descendants, and they exhibit much less variability. They enable the stereochemical affiliation of individual hydrogen atoms to be traced back first to the parent atoms in the common intermediate, geranyl diphosphate, then to the glyceraldehyde 3-phosphate and pyruvate couple involved in the DOXP pathway, and ultimately to the glucose precursor. The results illustrate the aptitude of the site-specific isotope ratios not only to authenticate natural with respect to chemical molecules but also to characterize different metabolic pathways and to reveal differences associated with the nature of the plant precursor.

US$19.90

PMID: 17177548

DOI: 10.1021/jf061979w


Other references

Clark, D.; White, N.; Robson, W., 2014: Student life--safety is a team effort. Nursing Standard 1987) 28(10): 66-66

Anonymous, 2000: Prevention of infections associated with the use of catheters. Soins; la Revue de Reference Infirmiere: 9-9

Griffin, G.E., 1993: The intestine and human immunodeficiency virus. Journal of Medical Microbiology 38(1): 1-2

Cargill, R.I.; Coutie, W.C.; Mcfarlane, L.C.; Lipworth, B.J., 1994: Effect of ANP and BNP on the pressor and aldosterone responses to angiotensin II. British Journal of Clinical Pharmacology 37(5): 487P

Spoormaker, V.I.; Czisch, M.; Maquet, P.; Jäncke, L., 2012: Large-scale functional brain networks in human non-rapid eye movement sleep: insights from combined electroencephalographic/functional magnetic resonance imaging studies. This paper reviews the existing body of knowledge on the neural correlates of spontaneous oscillations, functional connectivity and brain plasticity in human non-rapid eye movement (NREM) sleep. The first section reviews the evidence that specific...

Szabo, S.T.; Blier, P., 2002: Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons. YM992 ((S)-2-(((7-fluoro-4-indanyl)oxy)methyl)morpholine monohydrochloride) is a selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitor (SSRI) and a potent 5-HT2A antagonist. The aim of the present study was to assess, using in vivo ex...

Meck, J.M.; Kramer Dugan, E.; Matyakhina, L.; Aviram, A.; Trunca, C.; Pineda-Alvarez, D.; Aradhya, S.; Klein, R.T.; Cherry, A.M., 2015: Noninvasive prenatal screening for aneuploidy: positive predictive values based on cytogenetic findings. We sought to determine the positive predictive value (PPV) of noninvasive prenatal screening (NIPS) for various aneuploidies based on cases referred for follow-up cytogenetic testing. Secondarily, we wanted to determine the false-negative (FN) rat...

Lu, G.; Yang, M.; Shen, Y.; Meng, J., 1991: The absorption of Fe, Zn, Cu in siwu, sijunzi, and Liuwei dihuang decoction by small intestine in rats. In this study the absorption of Fe, Zn and Cu in decoctions of siwu decoction, sijunzi decoction and liuwei dihuang decoction by the small intestine in anesthetized rats was observed. The experimental results showed that the absorption of Cu and F...

Rymer, C.; Gibbs, R.A.; Givens, D.I., 2010: Comparison of algal and fish sources on the oxidative stability of poultry meat and its enrichment with omega-3 polyunsaturated fatty acids. Human consumption of long-chain n-3 polyunsaturated fatty acids (LC n-3 PUFA) is below recommendations, and enriching chicken meat (by incorporating LC n-3 PUFA into broiler diets) is a viable means of increasing consumption. Fish oil is the most...

Anonymous, 2003: Dairy Statistics - Livestock Improvement Corporation Limited, 2001-2002. This paper contains the national dairy statistics (industry and farm production), regional dairy statistics, herd improvement (herd testing and breeding), general statistics (prices, breeds, calving dates and operating structures) and disease cont...