geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Toxoplasma gondii: differential protection rates by two strains against cyst formation in a rat model


, : Toxoplasma gondii: differential protection rates by two strains against cyst formation in a rat model. Experimental Parasitology 114(4): 265-270

A previous infection with the ME-49 strain of Toxoplasma gondii (of low pathogenicity for mice), protected 17 of 20 rats against formation of brain cysts, following challenge with 10(3) oocysts of the high pathogenicity M3 strain, as determined by bioassay of rat brains in mice. The low pathogenic KSU strain did not afford comparable protection. Protection was further tested in rats that were orally or subcutaneously immunized with cysts or oocysts of the ME-49 strain, and later challenged with 2 x 10(2) cysts or 10(2) oocysts of the highly pathogenic strains M3, M-7741 and C. Protection ranged from 43 to 100%, compared to non immunized control rats and was independent of the stage of ME-49 strain and of the routes used to immunize the rats. The results obtained encourage further investigation into prevention of toxoplasmosis in humans and food animals.

US$19.90

PMID: 16709408

DOI: 10.1016/j.exppara.2006.04.002


Other references

Shaldon, S.; Lazarus, J.M.; Lundin, A.P.; Tzamaioukas, A.H.; Oreopoulos, O.G.; Kjellstrand, C.M., 2000: How can survival of the well-dialyzed patient be increased?. Seminars in Dialysis 13(1): 11-22

Ginsberg, J.S.; Siragusa, S.; Douketis, J.; Johnston, M.; Moffat, K.; Donovan, D.; McGinnis, J.; Brill-Edwards, P.; Panju, A.; Patel, A.; Weitz, J.I., 1996: Evaluation of a soluble fibrin assay in patients with suspected pulmonary embolism. In order to determine the clinical utility of an enzyme immunoassay (EIA) for soluble fibrin in patients with suspected pulmonary embolism (PE), 195 unselected patients with suspected PE underwent blood sampling for measurement of plasma levels of...

Paquet, L.; Bergeron, F.; Boudreault, A.; Seidah, N.G.; Chrétien, M.; Mbikay, M.; Lazure, C., 1994: The neuroendocrine precursor 7B2 is a sulfated protein proteolytically processed by a ubiquitous furin-like convertase. The neuroendocrine granule-associated protein 7B2, unlike many other neuroendocrine precursor proteins stored in secretory granules, carries in its primary structure the Arg-Xaa-Arg/Lys-Arg processing site usually found in constitutively secreted...

Kricheldorff, H., 1963: Nasal Enlargement Caused By An Extremely Large Lacrimal Recess Of The Maxillary Sinus. Hno 11: 265-266

Schmid-Hempel, R., 1984: The importance of handling time for the flight directionality in bees. Individual workers of the honeybee (A. mellifera), trained to collect food from a patch of artificial flowers, were used to test the following hypotheses about the mechanism leading to a decrease in flight directionality when moving from 1 flower...

Naranjo, C.; Poggio, L., 1988: A comparison of karyotype, Ag-NOR bands and DNA content in Amaryllis and Hippeastrum (Amaryllidaceae). Kew bulletin3(2): 317-325

Avanzini Marco, 1992: Structural evolution of the compressed zone between Riva del Garda and Roverto, Southern Alps. Memorie di Scienze Geologiche: ages 13-25. 1992.

Anonymous, 1987: Standards of practice for occupational therapy services in schools. American Journal of Occupational Therapy 41(12): 804-808

Hmami, F.; Chaouki, S.; Benmiloud, S.; Souilmi, F.Z.; Abourazzak, S.; Idrissi, M.; Atmani, S.; Bouharrou, A.; Hida, M., 2015: Seizures revealing phosphocalcic metabolism abnormalities. Hypocalcemia due to hypoparathyroidism produces a broad spectrum of clinical manifestations, but overt symptoms may be sparse. One unusual presentation is onset or aggravation of epilepsy in adolescence revealing hypoparathyroidism. This situation...

Berger, P.H.; Wyatt, S.D., 1993: Phylogenetic analysis of bean common mosaic potyvirus strains. Phytopathology 83(12): 1374