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Positive serological tests for syphilis and administration of intravenous immunoglobulin

, : Positive serological tests for syphilis and administration of intravenous immunoglobulin. Sexually Transmitted Infections 83(1): 57-58

We report the case of a man who tested positive for syphilis following the intravenous administration of human normal immunoglobulin as part of the treatment of Guillain-Barre syndrome. The chronology of the testing suggested the passive acquisition of treponemal antibody. This phenomenon is not widely documented in the medical literature, but is a theoretical risk of treatment, and serves as a reminder to be cautious in the interpretation of such serological tests.


PMID: 17283361

DOI: 10.1136/sti.2006.020503

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