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Comparative analysis of triterpenoids from Mikania cordifolia collected from four different locations

, : Comparative analysis of triterpenoids from Mikania cordifolia collected from four different locations. Revista Brasileira de Ciencias Farmaceuticas 42(4): 547-552

The species Mikania cordifolia is distributed across America and widely found throughout Brazilian territory, where is popularly used against snake bites. Methanolic and dichloromethanic extracts prepared from M. cordifolia Robinson collected from four different locations in Brazil were submitted to liquid- liquid extraction and the hexanic phase and residues obtained from this step were anaylzed for triterpenoids by gas chromatography. The specimens from Ribeirao Preto-SP and Sao Carlos-SP showed similar triterpenoid composition: alpha-amyrin, lupeol, lupenone, alpha-amyrin acetate, beta-amyrin acetate, taraxasterol acetate, campesterol and beta-sitosterol. Besides these triterpenoids, the specimen from Campos de Jardao-SP presented 11-oxours-12-ene, 11-oxoolean-12-ene and taraxerol acetate, and from Monte Verde, epetaraxerol e taraxerol acetate. The triterpene friedelin could be found in specimens from Ribeirao Preto and Sao Carlos.


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