geoscience.net logo
+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

Towards a validation of a cellular biomarker suite in native and transplanted zebra mussels: a 2-year integrative field study of seasonal and pollution-induced variations


, : Towards a validation of a cellular biomarker suite in native and transplanted zebra mussels: a 2-year integrative field study of seasonal and pollution-induced variations. Aquatic Toxicology 81(4): 377-388

Two of the questions raised in the validation process of biomarkers are their relevance in the identification and discrimination of environmental perturbations, and the influence of seasonal factors on these biological endpoints. Determining the advantages and restrictions associated with the use of native or transplanted animals and comparing their responses is also needed. To obtain this information, a 2-year integrative field study was conducted in the vicinity of a nuclear power plant in northeastern France. A station was located in the reservoir receiving the cooling waters of the plant, and two other sites were studied 2 km upstream and 5 km downstream from the reservoir's discharge in the Moselle river. Elevated temperatures, copper contamination and a 1.4-fold-concentration factor of dissolved salts affected water quality of the reservoir. Native and transplanted zebra mussels (Dreissena polymorpha) were collected monthly and their digestive glands were processed for histochemical determinations of the lysosomal and peroxisomal systems and of the lipofuscin and neutral lipid contents. The responses were quantified using automated image analysis and stereology. Apart from neutral lipid contents, there were no systematic seasonal patterns in mussel populations or from I year to another. Principal Component Analyses showed a general higher discrimination potential of biological responses in transplanted organisms compared to native ones. They also pointed out the relationships between the cellular and physiological markers and abiotic factors. The present multiple biomarker integrative approach in transplanted D. polymorpha brings promising elements in their validation process as relevant biomonitoring tools.

US$19.90

PMID: 17313981

DOI: 10.1016/j.aquatox.2006.12.016


Other references

Pascual, R.; Mcgovern, J.P., 1952: Febrile convulsions in childhood; a statistical analysis of the clinical features in 455 cases. Clinical Proceedings - Children's Hospital of the District of Columbia 8(5): 92-98

Bernardo Cervantes-Sodi; X.H.rnandez; H.S.ong Hwang; Changbom Park; Damien L.B.rgne, 2012: The spin of late-type galaxies at redshifts z ? 12. We study the evolution of the galactic spin using data of high-redshift galaxies in the fields of the Great Observatories Origins Deep Survey. Through simple dynamical considerations we estimate the spin for the disc galaxies in our sample and fin...

Scharer L.; Hemmerle C.; Celio M.R., 1986: Immunohistology on semithin cryo sections. Experientia (Basel) 42(6): 676-677

Dehpour, A.R.; Zolfaghari, M.E.; Samadian, T.; Vahedi, Y., 1994: The protective effect of liquorice components and their derivatives against gastric ulcer induced by aspirin in rats. We have examined the protective effect of liquorice or its derivatives against gastric ulcer induced by aspirin. A granular mixture of aspirin alone and coated with liquorice or its derivatives including the deglycyrrhized form, a high glycyrrhize...

Jones G., 1982: Failure of 1 25 di hydroxy vitamin d 3 alone to heal rickets due to vitamin d deficiency. Calcified Tissue Internationalppl. 1: S51

Cice, G.; Ferrara, L.; Tagliamonte, E.; Russo, P.E.; D.B.nedetto, A.; Iacono, A., 2000: Angiotensin-II receptor inhibitors in hemodialysed uremia patients with arterial hypertension: candesartan cilexitil versus losartan. The aim of this study was to evaluate, in patients with chronic renal failure in hemodialysis and arterial hypertension, the effectiveness of a new angiotensin II receptor antagonist, the candesartan cilexitil, comparing it with losartan, the firs...

Peschier, L.J.; Bouwstra, J.A.; de Bleyser, J.; Junginger, H.E.; Leyte, J.C., 1993: Water mobility and structure in poly[2-hydroxyethylmethacrylate] hydrogels by means of the pulsed field gradient NMR technique. The translational mobility of water in poly[2-hydroxyethylmethacrylate] (pHEMA) hydrogels, cross-linked with ethyleneglycoldimethacrylate, was studied by means of the pulsed field gradient (PFG) nuclear magnetic resonance (NMR) technique, which of...

Pincha Elizabeth M.W., 1987: Monitoring effects of the Mount St. Helens eruptions on the Toutle River drainage basin. Pages 24-69 1987

Mohsin, S.; Khan, M.; Toko, H.; Bailey, B.; Cottage, C.T.; Wallach, K.; Nag, D.; Lee, A.; Siddiqi, S.; Lan, F.; Fischer, K.M.; Gude, N.; Quijada, P.; Avitabile, D.; Truffa, S.; Collins, B.; Dembitsky, W.; Wu, J.C.; Sussman, M.A., 2012: Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. The study goal was to demonstrate the enhancement of human cardiac progenitor cell (hCPC) reparative and regenerative potential by genetic modification for the treatment of myocardial infarction. Regenerative potential of stem cells to repair acut...

Cacicedo L.; Sanchez Franco F.; Reichlin S., 1978: Different effect of thyroid hormones on adreno corticotropin and thyrotropin biosynthesis by rat pituitaries. Annales d'Endocrinologie 39(5): 6A