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Clinical significance of diffusion-weighted MRI with STIR-EPI in differential diagnosis of cervical lymph nodes

, : Clinical significance of diffusion-weighted MRI with STIR-EPI in differential diagnosis of cervical lymph nodes. Zhonghua Zhong Liu Za Zhi 29(1): 70-73

Objective To evaluate the feasibility and efficacy of a new MRI imaging method-diffusion weighted imaging (DWI) with short TI version recovery-echo planar imaging (STIR-EPI) sequence in differentiating benign cervical lymph nodes from malignant ones. Methods Twenty nasopharyngeal carcinoma patients and fourteen volunteers received both conventional MRI and DWI with STIR-EPI. Ability of detecting lymph nodes between conventional MRI and STIR-EPI-DWI was compared, and the difference of apparent diffusion coefficient ( ADC) value between metastatic lymph node and normal lymph node was analyzed. Results DWI was more sensitive in detecting lymph node than conventional MRI. ADC value of metastatic lymph node (0.766 +/- 0.119) x 10(-3) mm(2)/s was significantly lower than that of normal lymph node (0.975 +/- 0. 179) x 10(-3) mm(2)/s (P < 0.01). Conclusion As a new MRI imaging technique in detecting cervical lymph nodes, diffusion weighted imaging ( DWI) with short TI version recovery-echo planar imaging ( STIR-EPI) sequence is more reliable and sensitive than conventional MRI imaging, providing an alternative way to differentiate benign lymph nodes from malignant ones.


PMID: 17575700

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