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Phosphonoxins: rational design and discovery of a potent nucleotide anti-Giardia agent

, : Phosphonoxins: rational design and discovery of a potent nucleotide anti-Giardia agent. Bioorganic & Medicinal Chemistry Letters 17(10): 2811-2816

Phosphonoxins, a new class of synthetic, rationally designed anti-microbial agents, are described. From this class a submicromolar inhibitor of Giardia trophozoite growth has been identified.


PMID: 17360182

DOI: 10.1016/j.bmcl.2007.02.063

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