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Fatty acid oxidation by carp liver mitochondria


, : Fatty acid oxidation by carp liver mitochondria. Archives of Biochemistry and Biophysics 85: 149-158

Carp liver mitochondria were shown to contain an enzyme system that will oxidize fatty acids in the presence of adenosine triphosphate, cytochrome c, and Mg++. The addition of a small amount of a tricarboxylic acid cycle intermediate enhanced the rate of oxidation. Fatty acids readily oxidized included butyrate, octanoate, palmitate, oleate, linoleate, arachidonate, eicosapentaenoate, and docosahexaenoate. The effect of adding various activators, cofactors, and inhibitors was reported. Acetoacetate was produced in less than theoretical amounts from the oxidation of linoleate and in approximately theoretical amounts from the oxidation of octanoate.

US$19.90

PMID: 13805045

DOI: 10.1016/0003-9861(59)90458-8


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