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Ocular toxicity of Whipcide (3-methyl-i-pentyn-3-yl acid phthalate) in humans


, : Ocular toxicity of Whipcide (3-methyl-i-pentyn-3-yl acid phthalate) in humans. Journal of the American Medical Association. 161: 13, 1252-1253

Whipcide given daily to 143 adult Hondurans in doses of 20 to 145 mg. per kg. body-weight for four to five days was only 22% effective against Trichuris trichiura. A 50% cure rate was obtained by single doses of 100 to 200 mg. per kg., but 9.5% of the patients developed temporarily severe conjunctivitis and keratitis. The seven patients who received a single dose of 200 mg. were all cured but all developed ocular complications.

US$29.90

PMID: 13331790


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