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The resin-agglutination test for vesicular stomatitis

, : The resin-agglutination test for vesicular stomatitis. American Journal of Veterinary Research 19(72): 761-764

A good correlation was observed between the neutralization and the resin agglutination-inhibition (Segre, D., Jour. Immunol. 78: 304, 1957) titers of 43 serums with antibodies to vesicular stomatitis virus. Resin-agglutination titers of tissues and fluid from chicken embryos inoculated with vesicular stomatitis virus indicated that the viral antigen was more abundant and appeared earlier in the embryo than in the chorioallantoic membrane or the allantoic fluid. No correlation was found between infectivity and resinagglutination titers. A marked cross reaction between the 2 immunological types of vesicular stomatitis virus was observed. Treatment of the virus with heat or formalin destroyed its infectivity but not its antigenicity as detected with the resin-agglutination test. The possibility is discussed that the viral antigen detected by resin-agglutination might be separated from the infectious viral particles.


PMID: 13559636

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