+ Resolve Article
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter

+ Translate
+ Subscribe to Site Feed
GeoScience Most Shared ContentMost Shared Content

The response of hamsters to a natural-type diet containing emulsifiers

, : The response of hamsters to a natural-type diet containing emulsifiers. Food Res 22(3): 273-286

Two ex-periments are reported in which a hydrogenated vegetable oil (Primex), polyoxyethylene (8) monostearate (Myrj 45), a mixture of meat and vegetable monoglycerides and diglycerides (Esterine) and cottonseed oil monoglycerides (Myverol 18-85) were fed to hamsters at varying levels from 5 to 20% of a diet composed of natural ingredients and simulating the American diet for varying periods up to 10 weeks. No abnormalities in behavior or physical appearance were observed in any of the hamsters at any time during the feeding periods. Diarrhea was not observed in any of the groups and no mortality was attributable to diet. No significant differences in weight gains were noted among the 3 groups fed Myrj 45, Esterine, or Myverol 18-85 although all groups grew at a somewhat retarded rate compared with the group fed Primex. Although with Myrj 45 at the 20% level growth was somewhat retarded, the combination of 10% Primex and 10% Myrj 45 resulted in a rate of gain and efficiency of calorie utilization equal to that of the 20% Primex group. The high voluntary food intake of the Myrj 45 group was related to the low calorie density of that diet. The gross appearance of the animals, both external and internal, was normal although the ceca and kidneys of the Myrj 45 group were somewhat enlarged. Microscopic studies demonstrated the absence of pathology in the following organs: liver, kidney, duodenum, ileum, and cecum. The lack of harmful effects upon feeding polyoxyethylene (8) monostearate (Myrj 45) to hamsters at dietary levels as high as 20% confirms the conclusion reached by other investigators working with man as well as with experimental animals, that no hazard may be expected from the proposed use of this emulsifier to the extent of a few tenths of 1% in the human diet.


DOI: 10.1111/j.1365-2621.1957.tb17011.x

Other references

Nakase, G.; Nakagawa, Y.; Miyashita, S.; Nasu, T.; Senoo, S.; Matsubara, H.; Eguchi, M., 2007: Association between bacterial community structures and mortality of fish larvae in intensive rearing systems. Bacterial community structures were analyzed in water used for rearing fish larvae by fluorescence in situ hybridization. In Experiment 1, red sea bream Pagrus major larvae were reared in two commercial seed production tanks. The survival rate in...

Puth, A.D., 1974: More heat than light. Journal of Rehabilitation 40(1): 2-2

Schreiber, R.; Byrne-Coker, E., 1991: Nursing case conferences on a psychiatric unit. Nursing Management 22(10): 102, 120-102, 120

Finland, M., 1972: Global epidemiology - stocktaking at WHO. New England Journal of Medicine 287(11): 565-566

Boutros, A.; Laporte, J.P., 1992: Postoperative death of a patient with a giant meningioma. Annales Francaises D'anesthesie et de Reanimation 11(4): 475-475

Sheikh, H.S.; Tiangco, N.Dexter.; Harrell, C.; Vender, R.L., 2012: Severe hypercapnia in critically ill adult cystic fibrosis patients. Cystic fibrosis (CF) is a monogenetic autosomal recessive multi-organ disease affecting approximately 50,000 patients worldwide. Overall median survival is continually increasing but pulmonary disease remains the most common cause of death. Guidel...

Hammer M.; Wallwork J.A., 1979: A review of the world distribution of oribatid mites acari cryptostigmata in relation to continental drift. A survey is presented of the patterns of world distribution of oribatid mites, mainly at the generic level. The oribatids are probably an ancient group, and recent genera have an evolutionary history extending back to the Jurassic and probably ear...

Moran, JB.; Hill, D.; Geren, CR., 1981: Comparison of three phospholipases isolated from copperhead venoms. 1.1. Three phospholipases were purified by molecular sieve chromatography from ion-exchange fractions obtained from whole copperhead snake (Agkistrodon contortrix) venoms.2.2. In comparing the three phospholipases, one acidic and two basic, all ha...

Schafrank, S.N.; Kurban, A.K.; Martone, G., 1990: Lyme disease acquired in southeast Africa. A 31-year old white male (from Massachusetts, USA) suffered tick bites (species not stated) while in Tanzania, following which he developed an asymptomatic papular eruption over the chest. Biopsy of a lesion revealed a superficial and deep perivas...

Willocks, J., 1967: A symposium on clinical problems of practice. Foetal distress in labour. Journal of the College of General Practitioners 13 Suppl 1: :47-:52