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On the clinical course and treatment of patients with extensive mycoses caused by Trichophyton rubrum


, : On the clinical course and treatment of patients with extensive mycoses caused by Trichophyton rubrum. Vest. Derm. Vener, 41: 4, 47-52

The clinical course of 58 patients was frequently accompanied by ichthyosis, disorders in the endocrine, cardio-vascular, and nervous systems, decrease in ascorbic acid, and increase in pyruvic acid. Griseofulvin treatment was most effective in combination with local therapy (vitamin A, paraffin, treatment of accompanying diseases). During treatment half the patients showed an increase in pyruvic acid in the blood and it was excreted in the urine.

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