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Effects of pH on the acute toxicity and uptake of [14C]pentachlorophenol in the midge, Chironomus riparius


, : Effects of pH on the acute toxicity and uptake of [14C]pentachlorophenol in the midge, Chironomus riparius. Ecotoxicology and Environmental Safety 11(1): 1-8

The acute toxicity of pentachlorophenol (PCP) was determined at pH levels 4, 6, and 9 to the midge, Chironomus riparius, with the findings that PCP is of greatest toxicity at pH 4 and of least toxicity at pH 9. This differential toxicity is attributable to variations in uptake levels at the respective pH levels. At pH 4, PCP is fully protonated and therefore highly lipophilic. The amount of [14C]PCP present in the midges at 24 hr is thus highest at pH 4. Conversely, at pH 9, the compound is completely ionized. The reduction in lipophilicity at pH 9 decreases the ability of the compound to penetrate into the midge, thereby decreasing the observed toxicity of the compound.

US$19.90

PMID: 3956426

DOI: 10.1016/0147-6513(86)90023-0


Other references

D.S.rvi, S.; Ricevuti, G.; Mazzone, A.; Pasotti, D.; Bramucci, E.; Angoli, L.; Specchia, G., 1991: Transcardiac release of leukotriene C4 by neutrophils in patients with coronary artery disease. Leukotriene C4 is a potent constrictor of smooth muscle in vitro and may induce coronary vasoconstriction in vivo. To study leukotriene C4 release by neutrophils in patients with coronary artery disease, neutrophils were separated from blood sampl...

Venkateswarlu, K.; Preethi, J.Komala.; Chandrasekhar, K.Bonnoth., 2016: Enhancement of Loperamide Dissolution Rate by Liquisolid Compact Technique. NlmCategory="UNASSIGNED"><b><i>Purpose:</i></b> The aim of present study was to improve the dissolution rate of poorly soluble drug Loperamide (LPM) by liquisolid compact technique. <b><i>Methods:&l...

Spurr E.B., 1985: Records of chinstrap penguins pygoscelis antarctica in the ross sea region antarctica. Notornis: 1-4

Phogat, S.B.; Mehar Singh; Singh, R.C., 1991: Crop weed competition in pigeon pea, Cajanus cajan (L.) Millsp. Field trials were conducted on sandy loam in Haryana in kharif 1984 and 1986 to evaluate the effects of maintaining pigeon peas cv. Manak intercropped with mungbeans [Vigna radiata] cv. K-851 in a weed-free condition for various periods up to 60 d...

Leung-Pineda, V.; Wilson, D.P., 2016: Severe Hypercholesterolemia and Cutaneous Xanthomas in a 3-Year-Old Boy. Clinical Chemistry 62(6): 899-900

Calaluce, R.; Bearss, D.J.; Barrera, J.; Zhao, Y.; Han, H.; Beck, S.K.; McDaniel, K.; Nagle, R.B., 2004: Laminin-5 beta3A expression in LNCaP human prostate carcinoma cells increases cell migration and tumorigenicity. Interactions between extracellular matrix proteins and prostate carcinoma cells change dramatically during prostate tumor progression. We have concentrated on two key modifications that occur in the hemidesmosome in prostate carcinoma: loss of lam...

Seidel, W.; Akutsu, T.; Mirkovitch, V.; Kolff, W.J., 1963: Intrathoracic artificial hearts. Thoraxchirurgie 10: 446-465

Castelli, Vero, 1941: Fluorescence of some pigments of microbial origin. Thesis: Fribourg: 6 Pl. Illus

Frohlich, E.D., 1987: Coexistence of hypertensive and coronary arterial disease. Hypertension 10(5): 473-475

Kitzmiller, J.L.; Tanenberg, R.J.; Aoki, T.T.; Tabatabaii, A.; Gleason, R.; Jewett, J.F.; Hare, J.W.; Soeldner, J.S., 1980: Pancreatic alpha cell response to alanine during and after normal and diabetic pregnancies. Pancreatic alpha cell response to oral alanine was assessed in the third trimester of pregnancy and in the puerperium in 16 insulin-dependent diabetic and 7 normal pegnant women. Insulin response was also measured in the nondiabetic subjects. The...